Two new benzophenones isolated from a mangrove-derived fungus Penicillium sp.
Acanthaceae
/ microbiology
Anti-Bacterial Agents
Benzophenones
/ isolation & purification
Biological Products
/ chemistry
Magnetic Resonance Spectroscopy
Mass Spectrometry
Methicillin-Resistant Staphylococcus aureus
/ drug effects
Microbial Sensitivity Tests
Molecular Structure
Penicillium
/ chemistry
Journal
The Journal of antibiotics
ISSN: 1881-1469
Titre abrégé: J Antibiot (Tokyo)
Pays: England
ID NLM: 0151115
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
received:
11
05
2021
accepted:
08
07
2021
revised:
08
07
2021
pubmed:
20
8
2021
medline:
15
12
2021
entrez:
19
8
2021
Statut:
ppublish
Résumé
One new benzophenone derivative, named penibenzophenone C (1), and a new benzophenone natural product, neamed penibenzophenone D (2), together with two known compounds (3, 4) were isolated from the EtOAc extract of the endophytic fungus Penicillium sp. isolated from the mangrove Acanthus ilicifolius L. collected in the South China Sea. The structures of 1-4 were elucidated by extensive NMR spectral interpretation and MS data. The new compounds 1 and 2 showed moderate antibacterial activities against methicillin-resistant Staphylococcus aureus with the MIC values of 3.12 and 6.25 μg ml
Identifiants
pubmed: 34408287
doi: 10.1038/s41429-021-00464-9
pii: 10.1038/s41429-021-00464-9
doi:
Substances chimiques
Anti-Bacterial Agents
0
Benzophenones
0
Biological Products
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
821-824Informations de copyright
© 2021. The Author(s), under exclusive licence to the Japan Antibiotics Research Association.
Références
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