Efficient Production of 2'-Fucosyllactose from l-Fucose

Dietary Supplements Escherichia coli / genetics Fucose / metabolism Genome, Bacterial Metabolic Engineering Multienzyme Complexes / metabolism Trisaccharides / biosynthesis
2′-fucosyllactose Escherichia coli cofactor regeneration fed-batch fermentation self-assembling multienzyme complex spatial synthetic biology

Journal

ACS synthetic biology
ISSN: 2161-5063
Titre abrégé: ACS Synth Biol
Pays: United States
ID NLM: 101575075

Informations de publication

Date de publication:
15 10 2021
Historique:
pubmed: 21 8 2021
medline: 3 3 2022
entrez: 20 8 2021
Statut: ppublish

Résumé

2'-Fucosyllactose (2'-FL) has been widely used as a nutritional additive in infant formula due to its multifarious nutraceutical and pharmaceutical functions in neonate health. As such, it is essential to develop an efficient and extensive microbial fermentation platform to cater to the needs of the 2'-FL market. In this study, a spatial synthetic biology strategy was employed to promote 2'-FL biosynthesis in recombinant

Identifiants

DOI: 10.1021/acssynbio.1c00102 PMID: 34415729
pubmed: 34415729
doi: 10.1021/acssynbio.1c00102
doi:

Substances chimiques

Multienzyme Complexes 0
Trisaccharides 0
Fucose 28RYY2IV3F
2'-fucosyllactose XO2533XO8R

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2488-2498

Auteurs

Li Wan (L)

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.

Yingying Zhu (Y)

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.

Geng Chen (G)

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.

Guocong Luo (G)

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.

Wenli Zhang (W)

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.

Wanmeng Mu (W)

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.
International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
ORCID: 0000-0001-6597-527X

Articles similaires

Comparative genomic analysis and characterization of novel high-quality draft genomes from the coal metagenome.

Arunmozhi Bharathi Achudhan, Lilly M Saleena
1.00
Coal Metagenome Phylogeny Bacteria Genome, Bacterial

From cactus to crop: genomic insights of a beneficial and non-pathogenic Curtobacterium flaccumfaciens strain and the evolution of its pathosystem.

Dilson Fagundes Ribeiro, Jéssica Pereira de Matos, Lorrana Cachuite Mendes Rocha et al.
1.00
Genome, Bacterial Virulence Phylogeny Genomics Plant Diseases

Dietary supplementation with xylanase suppresses the antinutritional effect of nonstarch polysaccharides of flaxseed and increases bone strength in broiler chickens.

Miloš Skřivan, Michaela Englmaierová, Milan Marounek et al.
1.00
Animals Flax Chickens Dietary Supplements Endo-1,4-beta Xylanases

Bioinspired gelated cell sheet-supported lactobacillus biofilm for aerobic vaginitis diagnosis and treatment.

Yueyue Gui, Qingfei Sun, Kexin Li et al.
1.00
Female Biofilms Animals Lactobacillus Mice

Classifications MeSH

questionsmedicales.fr › Aliments et boissons › Aliments › Compléments alimentaires › Efficient Production of 2'-Fucosyllactose from l-Fucose
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Escherichia › Escherichia coli › Efficient Production of 2'-Fucosyllactose from l-Fucose
questionsmedicales.fr › Glucides › Désoses › Fucose › Efficient Production of 2'-Fucosyllactose from l-Fucose
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome microbien › Génome bactérien › Efficient Production of 2'-Fucosyllactose from l-Fucose
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Ingénierie cellulaire › Génie métabolique › Efficient Production of 2'-Fucosyllactose from l-Fucose
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Complexes multienzymatiques › Efficient Production of 2'-Fucosyllactose from l-Fucose
questionsmedicales.fr › Glucides › Polyosides › Oligosaccharides › Triholosides › Efficient Production of 2'-Fucosyllactose from l-Fucose