Human astrovirus types 1, 4 and 5 circulating among children with acute gastroenteritis in a rural Brazilian state, 2010-2016.
Journal
Archives of virology
ISSN: 1432-8798
Titre abrégé: Arch Virol
Pays: Austria
ID NLM: 7506870
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
26
03
2021
accepted:
22
06
2021
pubmed:
22
8
2021
medline:
16
10
2021
entrez:
21
8
2021
Statut:
ppublish
Résumé
This study combined conventional epidemiology of human astroviruses. From 2010 to 2016, 232 stool samples from children under 5 years of age were screened using NGS and conventional RT-PCR followed by genetic analysis in order to investigate the genotypic diversity of classical human astrovirus (HAstV) circulating in Tocantins State, Brazil. HAstV was detected in 16 cases (6.9%). Seven specimens (43.7%; 7/16) were positive according RT-PCR and next-generation sequencing (NGS) to investigate the molecular to both NGS and RT-PCR. NGS and RT-PCR individually revealed six (37.5%; 6/16) and three (18.8%; 3/16) additional positive samples, respectively. Sequencing of the HAstV-positive samples revealed HAstV-1a (9/16), HAstV-4c (3/16), and HAstV-5c (4/16) lineages.
Identifiants
pubmed: 34417874
doi: 10.1007/s00705-021-05206-8
pii: 10.1007/s00705-021-05206-8
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3165-3172Subventions
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
ID : 2016/01735-2
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
ID : 2017/00021-9
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
ID : 2015/12944-9
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
ID : 2019/21706-5
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
ID : 2020/02469-0
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : 400354/2016-0
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR)
ID : 302677/2019-4
Organisme : Fundação de Amparo à Pesquisa do Estado de Alagoas (BR)
ID : 2020/11182-6
Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.
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