Pemphigus-associated cardiomyopathy: report of autoimmune myocarditis and review of literature.
Autoimmune myocarditis
Cardiomyopathy
Pemphigus
Journal
ESC heart failure
ISSN: 2055-5822
Titre abrégé: ESC Heart Fail
Pays: England
ID NLM: 101669191
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
revised:
11
05
2021
received:
09
03
2021
accepted:
01
06
2021
pubmed:
26
8
2021
medline:
29
10
2021
entrez:
25
8
2021
Statut:
ppublish
Résumé
Pemphigus is a rare disease characterized by bullous lesions of the skin and mucous membranes. The aetiology is autoimmune and related to the formation of IgG autoantibodies against desmogleins, which are structural proteins of desmosomes that ensure the stability of contacts between cells. Cardiac involvement in patients with pemphigus is poorly documented. We report the data in the literature on this topic and a case of pemphigus-associated autoimmune myocarditis with damage of intercalated disc responding to immunosuppressive therapy. The occurrence of cardiomyopathy with left ventricular dysfunction in patients affected by pemphigus should be appropriately screened with endomyocardial biopsy as it could be the myocardial extension of a potentially reversible autoimmune disorder.
Identifiants
pubmed: 34432378
doi: 10.1002/ehf2.13474
pmc: PMC8497363
doi:
Substances chimiques
Autoantibodies
0
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
3690-3695Informations de copyright
© 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.
Références
Am J Pathol. 2000 Feb;156(2):685-95
pubmed: 10666397
Eur Heart J. 2017 Sep 14;38(35):2649-2662
pubmed: 28655210
J Cell Biol. 2001 Aug 20;154(4):691-7
pubmed: 11514586
J Cell Biol. 1999 Feb 8;144(3):435-46
pubmed: 9971739
Dermatol Pract Concept. 2019 Jul 31;9(3):181-186
pubmed: 31384490
J Dermatol Sci. 2003 Jun;32(1):33-41
pubmed: 12788527
J Am Coll Cardiol. 2016 Jan 5;67(1):116-7
pubmed: 26764074
JACC Cardiovasc Imaging. 2014 Mar;7(3):254-63
pubmed: 24560214
J Am Acad Dermatol. 2003 Oct;49(4):599-608
pubmed: 14512903
An Bras Dermatol. 2019 Jul 29;94(3):264-278
pubmed: 31365654
ESC Heart Fail. 2021 Oct;8(5):3690-3695
pubmed: 34432378
Dermatology. 2002;204(2):161-2
pubmed: 11937752
J Am Acad Dermatol. 1990 May;22(5 Pt 1):851
pubmed: 2189911
Int J Dermatol. 2009 Feb;48(2):162-9
pubmed: 19200194
J Dermatolog Treat. 2021 Nov;32(7):855-859
pubmed: 31868046
Eur Heart J. 2009 Aug;30(16):1995-2002
pubmed: 19556262
Heart Rhythm. 2018 May;15(5):732-733
pubmed: 29369789
J Invest Dermatol. 2012 Jan;132(1):92-7
pubmed: 21850023
Heart Rhythm. 2018 May;15(5):725-731
pubmed: 29277685
Br J Dermatol. 2016 Jun;174(6):1290-8
pubmed: 26864457
J Dermatolog Treat. 2018 Dec;29(8):802-805
pubmed: 29668335
Jpn Heart J. 1998 Mar;39(2):211-20
pubmed: 9687829
Clin Exp Dermatol. 2011 Oct;36(7):703-7
pubmed: 21906124
J Clin Immunol. 2011 Dec;31(6):985-97
pubmed: 21796504
J Am Acad Dermatol. 2003 Oct;49(4):609-14
pubmed: 14512904