Ischemic hypoxic encephalopathy: The role of MRI of neonatal injury and medico-legal implication.


Journal

Forensic science international
ISSN: 1872-6283
Titre abrégé: Forensic Sci Int
Pays: Ireland
ID NLM: 7902034

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 21 12 2020
revised: 03 06 2021
accepted: 17 08 2021
pubmed: 30 8 2021
medline: 28 10 2021
entrez: 29 8 2021
Statut: ppublish

Résumé

Hypoxic ischemic encephalopathy is one of the major causes of neonatal death and neurological disability in the child, and represents the most common birth injury claim. Intrapartum asphyxia often leads to several long-term sequalae, such as cerebral palsy and/or developmental delay, epilepsy. Through the neuroimaging it's possible to identify and define the different lesioned pictures and provide useful elements to establish the moment in which the damage occurred; indeed, timing of injury is a key element in the legal arena. Magnetic resonance imaging (MRI) is emerging as one of the most important tools in identifying the etiologic of neonatal encephalopathy as well as in predicting long-term outcomes. The aim of this study is to evaluate all MRI tests performed in a group of infants and young patients with possible neonatal encephalopathy, in order to determine the role of MRI in perinatal hypoxic-ischemic damage and the specific patterns that can point towards a diagnosis of the time of the damage's onset. Another goal is to assess the role of MRI in cases subject to legal-medical ligation. Since the advent of hypothermic neuroprotection, new malpractice allegations have arisen, including the failure to initiate cooling in a timely manner. In all cases, documentation of the status of the baby at birth, including a thorough neurologic exam, can be extremely helpful to the later defence of a malpractice claim, which might occur years later.

Identifiants

pubmed: 34455399
pii: S0379-0738(21)00288-7
doi: 10.1016/j.forsciint.2021.110968
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110968

Informations de copyright

Copyright © 2021. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no conflict of interest.

Auteurs

Federico Midiri (F)

Department of Radiology, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy.

Corinne La Spina (C)

Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, Section of Legal Medicine, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy. Electronic address: corinne.laspina93@gmail.com.

Alberto Alongi (A)

Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, Section of Legal Medicine, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy.

Federica Vernuccio (F)

Department of Radiology, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy.

Marcello Longo (M)

Department of Radiology, University of Messina, Italy.

Antonina Argo (A)

Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, Section of Legal Medicine, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy.

Massimo Midiri (M)

Department of Radiology, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy.

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