Sequencing and characterization of an L-asparaginase gene from a new species of Penicillium section Citrina isolated from Cerrado.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
09 09 2021
09 09 2021
Historique:
received:
22
03
2021
accepted:
24
08
2021
entrez:
10
9
2021
pubmed:
11
9
2021
medline:
10
11
2021
Statut:
epublish
Résumé
The enzyme L-asparaginase (L-ASNase) is used in the treatment of Acute Lymphoblastic Leukemia. The preparations of this enzyme for clinical use are derived from bacterial sources and its use is associated with serious adverse reactions. In this context, it is important to find new sources of L-ASNase. In this work, the Placket-Burman Experimental Design (PBD) was used to determine the influence of the variables on the L-ASNase production then it was followed by a 2
Identifiants
pubmed: 34504186
doi: 10.1038/s41598-021-97316-1
pii: 10.1038/s41598-021-97316-1
pmc: PMC8429440
doi:
Substances chimiques
Antineoplastic Agents
0
Proline
9DLQ4CIU6V
Asparaginase
EC 3.5.1.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
17861Informations de copyright
© 2021. The Author(s).
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