Interactions between Viral Regulatory Proteins Ensure an MOI-Independent Probability of Lysogeny during Infection by Bacteriophage P1.


Journal

mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231

Informations de publication

Date de publication:
26 10 2021
Historique:
pubmed: 15 9 2021
medline: 20 1 2022
entrez: 14 9 2021
Statut: ppublish

Résumé

Phage P1 is a temperate phage which makes the lytic or lysogenic decision upon infecting bacteria. During the lytic cycle, progeny phages are produced and the cell lyses, and in the lysogenic cycle, P1 DNA exists as a low-copy-number plasmid and replicates autonomously. Previous studies at the bulk level showed that P1 lysogenization was independent of

Identifiants

pubmed: 34517752
doi: 10.1128/mBio.01013-21
pmc: PMC8546580
doi:

Substances chimiques

Viral Regulatory and Accessory Proteins 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0101321

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM107597
Pays : United States

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Auteurs

Kailun Zhang (K)

Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Center for Phage Technology, Texas A&M University, College Station, Texas, USA.

Kiara Pankratz (K)

Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.

Hau Duong (H)

Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.

Matthew Theodore (M)

Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Center for Phage Technology, Texas A&M University, College Station, Texas, USA.

Jingwen Guan (J)

Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Molecular and Environmental Plant Sciences, Texas A&M University, College Station, Texas, USA.

Anxiao Andrew Jiang (AA)

Department of Computer Science and Engineering, Texas A&M University, College Station, Texas, USA.

Yiruo Lin (Y)

Department of Computer Science and Engineering, Texas A&M University, College Station, Texas, USA.

Lanying Zeng (L)

Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Molecular and Environmental Plant Sciences, Texas A&M University, College Station, Texas, USA.

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Classifications MeSH