Are Cutibacterium acnes present at the end of primary shoulder prosthetic surgeries responsible for infection? Prospective study.
Aged
Aged, 80 and over
Arthroplasty
/ adverse effects
Female
Genome, Bacterial
Gram-Positive Bacterial Infections
/ microbiology
Humans
Male
Middle Aged
Postoperative Complications
/ microbiology
Propionibacterium acnes
/ genetics
Prospective Studies
Shoulder
/ microbiology
Shoulder Prosthesis
/ microbiology
Bone and joint infection
Cutibacterium acnes
Shoulder prosthesis
Whole Genome Sequencing
Journal
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
ISSN: 1435-4373
Titre abrégé: Eur J Clin Microbiol Infect Dis
Pays: Germany
ID NLM: 8804297
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
08
07
2021
accepted:
07
09
2021
pubmed:
19
9
2021
medline:
27
1
2022
entrez:
18
9
2021
Statut:
ppublish
Résumé
The purpose of this study was to investigate if the C. acnes present at the end of a primary shoulder arthroplasty could be responsible for shoulder arthroplasty infection. Prospective study includes patients undergoing primary shoulder arthroplasty from January 2015 until December 2018. From all the patients included, 5 to 12 tissue samples were obtained and were specifically cultured to detect the presence of C. acnes. DNA was extracted from the C acnes isolated colonies and Whole Genome Sequencing (WGS) analysis was done. A cohort of 156 patients was finally included. In twenty-seven patients, the C. acnes was present at the end of the primary surgery. Two of these patients developed a C. acnes periprosthetic shoulder infection at 6 and 4 months after the primary surgery. WGS of C. acnes isolated colonies showed that all the revision-surgery isolates clustered near to the corresponding primary-surgery isolates compared to the other independent bacterial colonies. (99.89% of similarity). C. acnes present at the end of the primary surgery can be the cause of early or delayed periprosthetic joint infections in shoulder arthroplasty.
Identifiants
pubmed: 34535842
doi: 10.1007/s10096-021-04348-6
pii: 10.1007/s10096-021-04348-6
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
169-173Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
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