Synthetic Analogue of Butenolide as an Antifouling Agent.
antifouling compounds
butenolide
larval attachment assay
structural optimisation
Journal
Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729
Informations de publication
Date de publication:
25 Aug 2021
25 Aug 2021
Historique:
received:
21
06
2021
revised:
11
08
2021
accepted:
21
08
2021
entrez:
26
9
2021
pubmed:
27
9
2021
medline:
22
1
2022
Statut:
epublish
Résumé
Butenolide derivatives have the potential to be effective and environmentally friendly antifouling agents. In the present study, a butenolide derivative was structurally modified into Boc-butenolide to increase its melting point and remove its foul smell. The structurally modified Boc-butenolide demonstrated similar antifouling capabilities to butenolide in larval settlement bioassays but with significantly lower toxicity at high concentrations. Release-rate measurements demonstrated that the antifouling compound Boc-butenolide could be released from polycaprolactone-polyurethane (PCL-PU)-based coatings to inhibit the attachment of foulers. The coating matrix was easily degraded in the marine environment. The performance of the Boc-butenolide antifouling coatings was further examined through a marine field test. The coverage of biofouler on the Boc-butenolide coatings was low after 2 months, indicating the antifouling potential of Boc-butenolide.
Identifiants
pubmed: 34564143
pii: md19090481
doi: 10.3390/md19090481
pmc: PMC8465062
pii:
doi:
Substances chimiques
Carbamates
0
Polyesters
0
Polyurethanes
0
polycaprolactone
24980-41-4
butenolide
8KXK25H388
4-Butyrolactone
OL659KIY4X
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : the Hong Kong Branch of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
ID : SMSEGL20SC01
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