Cyclization and Self-Assembly of Cyclic Peptides.
Cyclic peptides
Nanotubes
Self-assembly
Solid-phase synthesis
Supramolecular chemistry
Journal
Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
1
10
2021
pubmed:
2
10
2021
medline:
6
1
2022
Statut:
ppublish
Résumé
Cyclic peptides are a fascinating class of molecules that can be programmed to fold or self-assemble into diverse mono- and multidimensional structures with potential applications in biomedicine, nanoelectronics, or catalysis. Herein we describe on-resin procedures to carry out head-to-tail peptide cyclization based on orthogonal protected linear structures. We also present essential characterization tools for obtaining dynamic and structural information, including the visualization cyclic peptide assembly into nanotubes (AFM, TEM) as well as the use of fluorescence microscopy.
Identifiants
pubmed: 34596863
doi: 10.1007/978-1-0716-1689-5_24
doi:
Substances chimiques
Peptides, Cyclic
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
449-466Informations de copyright
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.
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