Detection of whole genome selection signatures of Pakistani Teddy goat.

FST Hp statistics Pooled-seq Selection signatures TD Teddy goat

Journal

Molecular biology reports
ISSN: 1573-4978
Titre abrégé: Mol Biol Rep
Pays: Netherlands
ID NLM: 0403234

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 26 06 2021
accepted: 27 09 2021
pubmed: 6 10 2021
medline: 15 1 2022
entrez: 5 10 2021
Statut: ppublish

Résumé

Natural and artificial selection tend to cause variability that contributes to shape the genome of livestock in a way that differentiates them among the animal kingdom. The particular aim here is to identify positive selection signatures with whole genome pooled-sequence data of Pakistani Teddy goat. Paired-end alignment of 635,357,043 reads of Teddy goat with (ARS1) reference genome assembly was carried out. Pooled-Heterozygosity (Hp) and Tajima's D (TD) are applied for validation and getting better hits of selection signals, while pairwise F In brief, this study identified the genes under selection in Pakistani Teddy goat that will be helpful to refining the marker-assisted breeding policies and converging required production traits within and across other goat breeds and to explore full genetic potential of this valued species of livestock.

Sections du résumé

BACKGROUND BACKGROUND
Natural and artificial selection tend to cause variability that contributes to shape the genome of livestock in a way that differentiates them among the animal kingdom. The particular aim here is to identify positive selection signatures with whole genome pooled-sequence data of Pakistani Teddy goat.
METHODS AND RESULTS RESULTS
Paired-end alignment of 635,357,043 reads of Teddy goat with (ARS1) reference genome assembly was carried out. Pooled-Heterozygosity (Hp) and Tajima's D (TD) are applied for validation and getting better hits of selection signals, while pairwise F
CONCLUSIONS CONCLUSIONS
In brief, this study identified the genes under selection in Pakistani Teddy goat that will be helpful to refining the marker-assisted breeding policies and converging required production traits within and across other goat breeds and to explore full genetic potential of this valued species of livestock.

Identifiants

pubmed: 34609690
doi: 10.1007/s11033-021-06726-x
pii: 10.1007/s11033-021-06726-x
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7273-7280

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer Nature B.V.

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Auteurs

Rashid Saif (R)

Decode Genomics, Punjab University Employees Housing Scheme, Lahore, Pakistan. rashid.saif37@gmail.com.

Jan Henkel (J)

Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Tania Mahmood (T)

Decode Genomics, Punjab University Employees Housing Scheme, Lahore, Pakistan.

Aniqa Ejaz (A)

Decode Genomics, Punjab University Employees Housing Scheme, Lahore, Pakistan.

Fraz Ahmad (F)

Decode Genomics, Punjab University Employees Housing Scheme, Lahore, Pakistan.

Saeeda Zia (S)

Department of Sciences and Humanities, National University of Computer and Emerging Sciences, Lahore, Pakistan.

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