Assessment of preoperative and postoperative l-lactatemia and clinical outcomes in goats undergoing tube cystostomy: A retrospective study of 34 cases (2015-2020).
calcium carbonate
cystolithiasis
heart rate
potassium
struvite
urethrolithiasis
Journal
Journal of veterinary internal medicine
ISSN: 1939-1676
Titre abrégé: J Vet Intern Med
Pays: United States
ID NLM: 8708660
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
revised:
07
09
2021
received:
02
06
2021
accepted:
10
09
2021
pubmed:
8
10
2021
medline:
24
12
2021
entrez:
7
10
2021
Statut:
ppublish
Résumé
Urolithiasis in small ruminants has a poor long-term prognosis, and long-term clinical outcomes are variable and unpredictable. To assess the accuracy of preoperative and postoperative blood l-lactate concentrations in predicting a negative outcome in goats undergoing tube cystostomy. Thirty-four male goats undergoing tube cystostomy. Retrospective study. Medical records of goats undergoing tube cystostomy from 2015 to 2020 were reviewed. Clinical variables recorded included signalment, procedures before surgery, urolith location and type, duration of hospitalization, and heart rate. PCV, plasma total protein, potassium, preoperative and postoperative blood l-lactate concentrations, preoperative and postoperative creatinine concentrations, and relative changes in blood l-lactate and creatinine concentrations over time were measured using heparinized blood. A negative outcome was defined as death or euthanasia from urolithiasis complications at 6 months after discharge. Negative outcomes as a function of independent clinical variables were evaluated using χ Median (95% confidence interval) preoperative, postoperative, and the relative change over time of blood l-lactate concentrations were 3.3 mmol/L (2.2, 4.8), 1.0 mmol/L (0.7, 1.3), and 0.4 mmol/L (-3.5, 3.2), respectively. Preoperative (P = 1), postoperative (P = .14), and the relative change over time (P = .63) of blood l-lactate concentrations were not significant predictors of a negative outcome. Furthermore, all other clinical variables measured were not significant predictors of a negative outcome (P > .05). Veterinarians should advise clients that clinical outcomes after tube cystostomy in goats are likely unpredictable.
Sections du résumé
BACKGROUND
BACKGROUND
Urolithiasis in small ruminants has a poor long-term prognosis, and long-term clinical outcomes are variable and unpredictable.
OBJECTIVES
OBJECTIVE
To assess the accuracy of preoperative and postoperative blood l-lactate concentrations in predicting a negative outcome in goats undergoing tube cystostomy.
ANIMALS
METHODS
Thirty-four male goats undergoing tube cystostomy.
METHODS
METHODS
Retrospective study. Medical records of goats undergoing tube cystostomy from 2015 to 2020 were reviewed. Clinical variables recorded included signalment, procedures before surgery, urolith location and type, duration of hospitalization, and heart rate. PCV, plasma total protein, potassium, preoperative and postoperative blood l-lactate concentrations, preoperative and postoperative creatinine concentrations, and relative changes in blood l-lactate and creatinine concentrations over time were measured using heparinized blood. A negative outcome was defined as death or euthanasia from urolithiasis complications at 6 months after discharge. Negative outcomes as a function of independent clinical variables were evaluated using χ
RESULTS
RESULTS
Median (95% confidence interval) preoperative, postoperative, and the relative change over time of blood l-lactate concentrations were 3.3 mmol/L (2.2, 4.8), 1.0 mmol/L (0.7, 1.3), and 0.4 mmol/L (-3.5, 3.2), respectively. Preoperative (P = 1), postoperative (P = .14), and the relative change over time (P = .63) of blood l-lactate concentrations were not significant predictors of a negative outcome. Furthermore, all other clinical variables measured were not significant predictors of a negative outcome (P > .05).
CONCLUSIONS AND CLINICAL IMPORTANCE
CONCLUSIONS
Veterinarians should advise clients that clinical outcomes after tube cystostomy in goats are likely unpredictable.
Identifiants
pubmed: 34617625
doi: 10.1111/jvim.16271
pmc: PMC8692210
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2926-2932Informations de copyright
© 2021 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.
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