Phase separating cell fate.

Cell Differentiation Cellular Reprogramming Genome Octamer Transcription Factor-3 / genetics

Journal

Cell stem cell
ISSN: 1875-9777
Titre abrégé: Cell Stem Cell
Pays: United States
ID NLM: 101311472

Informations de publication

Date de publication:
07 10 2021
Historique:
entrez: 8 10 2021
pubmed: 9 10 2021
medline: 26 10 2021
Statut: ppublish

Résumé

How master regulators such as Oct4 can shape 3D genome architecture during cell reprogramming remains poorly understood. In this issue of Cell Stem Cell, Wang et al. (2021) demonstrate that Oct4 undergoes phase separation to reconfigure TAD architecture for cell fate control.

Identifiants

DOI: 10.1016/j.stem.2021.09.012 PMID: 34624226
pubmed: 34624226
pii: S1934-5909(21)00388-X
doi: 10.1016/j.stem.2021.09.012
pii:
doi:

Substances chimiques

Octamer Transcription Factor-3 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

1677-1678

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Yu Fu (Y)

Laboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.

Yuanyue Shan (Y)

Laboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.

Mingfeng Zhang (M)

Laboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.

Duanqing Pei (D)

Laboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China. Electronic address: peiduanqing@westlake.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Phase separating cell fate.
questionsmedicales.fr › Phénomènes génétiques › Reprogrammation cellulaire › Phase separating cell fate.
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Phase separating cell fate.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à domaine POU › Facteurs de transcription Oct › Facteur de transcription Oct-3 › Phase separating cell fate.