Unique and Transdiagnostic Dimensions of Reward Functioning in Attention-Deficit/Hyperactivity Disorder and Alcohol Use Disorder Symptoms.


Journal

Alcohol and alcoholism (Oxford, Oxfordshire)
ISSN: 1464-3502
Titre abrégé: Alcohol Alcohol
Pays: England
ID NLM: 8310684

Informations de publication

Date de publication:
09 Jul 2022
Historique:
received: 30 07 2021
revised: 17 09 2021
accepted: 18 09 2021
pubmed: 12 10 2021
medline: 14 7 2022
entrez: 11 10 2021
Statut: ppublish

Résumé

Contemporary theories of attention-deficit/hyperactivity disorder (ADHD) and alcohol use disorder (AUD) emphasize core dysfunctions in reward-related processes and behaviors as pathognomonic characteristics. However, to date, it is unclear which domains of reward functioning are unique to ADHD versus AUD symptom dimensions, and which represent underlying shared correlates. The current study employed secondary data analyses from a large community sample of emerging adults (N = 602; 57.3% female) and novel transdiagnostic modeling (i.e. bi-factor confirmatory factor analyses and structural equation modeling) of ADHD, AUD and shared symptom dimensions to identify unique and common reward-related dimensions: environmental suppressors, reward probability, hedonic capacity, proportionate substance-related reinforcement and delay discounting. The presence of environmental suppressors was the only reward-related construct that correlated with the underlying ADHD-AUD shared dimension. The AUD symptom dimension was uniquely associated with proportionate substance-related reinforcement, whereas the ADHD symptom dimension was uniquely associated with limited reward probability. No significant associations were found for delay discounting or hedonic capacity. These novel findings highlight specific aspects of reward-related functioning in ADHD, AUD and shared symptom dimensions. In so doing, this work meaningfully advances theoretical conceptualizations of these two commonly co-occurring presentations and suggests future directions for research on transdiagnostic correlates. Future longitudinal studies should include clinical samples with diagnoses of AUD and ADHD to further identify underlying correlates over time.

Identifiants

pubmed: 34632479
pii: 6385013
doi: 10.1093/alcalc/agab070
pmc: PMC9270991
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

452-459

Subventions

Organisme : NIAAA NIH HHS
ID : R01 AA024930
Pays : United States
Organisme : NIAAA NIH HHS
ID : F31 AA027140
Pays : United States

Informations de copyright

© The Author(s) 2021. Medical Council on Alcohol and Oxford University Press. All rights reserved.

Références

J Atten Disord. 2012 Apr;16(3):221-34
pubmed: 21289233
Ann Clin Psychiatry. 2006 Jul-Sep;18(3):145-8
pubmed: 16923651
Psychol Bull. 1990 Mar;107(2):238-46
pubmed: 2320703
Alcohol Clin Exp Res. 2016 Dec;40(12):2685-2691
pubmed: 27805267
Multivariate Behav Res. 1990 Apr 1;25(2):173-80
pubmed: 26794479
Addict Behav. 2020 Oct;109:106475
pubmed: 32480282
Psychol Addict Behav. 2021 Nov;35(7):803-816
pubmed: 33600197
Neuron. 2019 Mar 6;101(5):779-782
pubmed: 30844398
Psychopharmacology (Berl). 2008 Aug;199(3):457-80
pubmed: 18311558
Exp Clin Psychopharmacol. 2014 Jun;22(3):222-8
pubmed: 24708144
Neuroscientist. 2020 Feb;26(1):87-99
pubmed: 30866712
Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Mar;2(2):180-187
pubmed: 28825048
J Atten Disord. 2019 Sep;23(11):1240-1250
pubmed: 27329487
Neuropsychiatr Dis Treat. 2016 Aug 25;12:2149-64
pubmed: 27601909
Behav Ther. 2011 Jun;42(2):249-62
pubmed: 21496510
Br J Psychiatry. 1995 Jul;167(1):99-103
pubmed: 7551619
J Consult Clin Psychol. 2019 Jul;87(7):657-669
pubmed: 31070386
J Psychiatr Res. 2015 Jun;65:124-30
pubmed: 25864641
Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Jul;1(4):316-325
pubmed: 27722208
Behav Res Ther. 2005 Jul;43(7):831-42
pubmed: 15896281
Addict Behav Rep. 2020 Feb 05;11:100262
pubmed: 32467851
J Atten Disord. 2008 May;11(6):652-63
pubmed: 17495239
Behav Ther. 2015 Mar;46(2):156-65
pubmed: 25645165
Psychol Med. 2005 Feb;35(2):245-56
pubmed: 15841682
Neuropharmacology. 2017 Jul 15;121:179-194
pubmed: 28454982
Psychol Methods. 2016 Jun;21(2):137-50
pubmed: 26523435
J Pers Assess. 2013;95(2):129-40
pubmed: 23030794
Drug Alcohol Depend. 2008 Jul 1;96(1-2):145-54
pubmed: 18403134
Eur Psychiatry. 2012 Jul;27(5):309-13
pubmed: 20934311
Psychopharmacology (Berl). 2011 Aug;216(3):305-21
pubmed: 21373791
Addict Behav. 2021 Jan;112:106649
pubmed: 32979691
Clin Psychol Rev. 2019 Jun;70:79-90
pubmed: 30991244
Psychol Bull. 1997 Jan;121(1):65-94
pubmed: 9000892

Auteurs

Lauren E Oddo (LE)

Department of Psychology, University of Maryland, 4094 Campus Dr, College Park, MD 20742, USA.

Samuel F Acuff (SF)

Department of Psychology, University of Memphis, 400 Innovation Dr, Memphis, TN 38111, USA.

Melanie B Arenson (MB)

Department of Psychology, University of Maryland, 4094 Campus Dr, College Park, MD 20742, USA.

Assaf Oshri (A)

Department of Human Development and Family Science, University of Georgia, 305 Sanford Dr. Athens, GA 30602, USA.

Andrea Chronis-Tuscano (A)

Department of Psychology, University of Maryland, 4094 Campus Dr, College Park, MD 20742, USA.

James MacKillop (J)

Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West | Hamilton, Ontario L8S4L8 Canada.

James G Murphy (JG)

Department of Psychology, University of Memphis, 400 Innovation Dr, Memphis, TN 38111, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH