[Genetically determined trehalase deficiency in various population groups of Russia and neighboring countries].
disaccharide absorption
intestinal malabsorption
intolerance
trehalose
Journal
Voprosy pitaniia
ISSN: 0042-8833
Titre abrégé: Vopr Pitan
Pays: Russia (Federation)
ID NLM: 2984870R
Informations de publication
Date de publication:
2021
2021
Historique:
received:
24
06
2021
accepted:
01
09
2021
entrez:
31
10
2021
pubmed:
1
11
2021
medline:
23
2
2022
Statut:
ppublish
Résumé
Due to the low specificity and sensitivity of non-invasive clinical tests trehalose malabsorption remained out of sight of gastroenterologists. Therefore, the specialists regard this disorder as rare. Trehalose became widely used in the food industry as a harmless sucrose substitute, sweetener and stabilizer. After the discovery of the trehalase gene (rs2276064 TREH), it was found that the A*TREH allele is the determinant of the disaccharide absorption disorders, and the allele's carriership may be high in some groups. There is not enough information on the A*TREH frequency in the population of Russia.
Identifiants
pubmed: 34719147
doi: 10.33029/0042-8833-2021-90-5-96-103
doi:
Substances chimiques
Trehalose
B8WCK70T7I
Trehalase
EC 3.2.1.28
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
rus
Sous-ensembles de citation
IM
Pagination
96-103Informations de copyright
Copyright© GEOTAR-Media Publishing Group.
Déclaration de conflit d'intérêts
The authors declare no overt and potential conflict of interest related to the publication of this article.