Effect of chlorhexidine gluconate on mechanical and anti-microbial properties of thermoplastic cassava starch.
Anti-Infective Agents, Local
/ chemistry
Aspergillus oryzae
/ drug effects
Bacillus cereus
/ drug effects
Candida albicans
/ drug effects
Chlorhexidine
/ analogs & derivatives
Escherichia coli
/ drug effects
Glycerol
/ chemistry
Magnetic Resonance Spectroscopy
/ methods
Manihot
/ chemistry
Solubility
Staphylococcus aureus
/ drug effects
Starch
/ chemistry
Temperature
Tensile Strength
Water
/ chemistry
Antimicrobial
Biopolymer
Manihot esculenta
chlorhexidine gluconate
Journal
Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156
Informations de publication
Date de publication:
01 Jan 2022
01 Jan 2022
Historique:
received:
05
07
2021
revised:
16
08
2021
accepted:
17
09
2021
entrez:
7
11
2021
pubmed:
8
11
2021
medline:
4
2
2022
Statut:
ppublish
Résumé
Antimicrobial thermoplastic starch (TPS) was developed using cassava starch, glycerol, and chlorhexidine gluconate (CHG) blend. CHG was added at concentrations of 1%, 5%, 10%, and 20% (wt./wt.) as an antimicrobial additive. The tensile strength and hardness of the blended samples increased with the chlorhexidine gluconate content, especially for 1% CHG. wt./wt. (12.6 MPa and 94, respectively). The TPS/CHG20 blend exhibited a large phase of CHG and recrystallization of TPS. The water solubility decreased with the addition of CHG. Nuclear magnetic resonance data confirmed a reaction between the hydroxyl groups of TPS and the amino groups of CHG. The TPS/CHG20% exhibited an inhibition zone for three bacterial types (Staphylococcus aureus, Escherichia coli, and Bacillus cereus) and three fungal types (Rhizopus oligosporus, Aspergillus oryzae, and Candida albicans). CHG acted simultaneously as a chain extender and an antimicrobial additive for TPS, improving its tensile strength, hardness, and anti-microbial properties.
Identifiants
pubmed: 34742417
pii: S0144-8617(21)01077-8
doi: 10.1016/j.carbpol.2021.118690
pii:
doi:
Substances chimiques
Anti-Infective Agents, Local
0
Water
059QF0KO0R
Starch
9005-25-8
chlorhexidine gluconate
MOR84MUD8E
Glycerol
PDC6A3C0OX
Chlorhexidine
R4KO0DY52L
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
118690Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.