α-Galactosidase a Deficiency in Fabry Disease Leads to Extensive Dysregulated Cellular Signaling Pathways in Human Podocytes.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
20 Oct 2021
Historique:
received: 24 08 2021
revised: 08 10 2021
accepted: 14 10 2021
entrez: 13 11 2021
pubmed: 14 11 2021
medline: 4 1 2022
Statut: epublish

Résumé

Fabry disease (FD) is caused by mutations in the α-galactosidase A (

Identifiants

pubmed: 34768768
pii: ijms222111339
doi: 10.3390/ijms222111339
pmc: PMC8583658
pii:
doi:

Substances chimiques

alpha-Galactosidase EC 3.2.1.22
ASAH1 protein, human EC 3.5.1.23
Acid Ceramidase EC 3.5.1.23
rab11 protein EC 3.6.1.-
rab GTP-Binding Proteins EC 3.6.5.2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Dr. Werner Jackstädt foundation
ID : XXX
Organisme : Innovative Medical Research
ID : LE211702

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Auteurs

Ulrich Jehn (U)

Department of Medicine D, Division of General Internal and Emergency Medicine, Nephrology, and Rheumatology, University Hospital Münster, 48149 Münster, Germany.

Samet Bayraktar (S)

Department of Medicine D, Division of General Internal and Emergency Medicine, Nephrology, and Rheumatology, University Hospital Münster, 48149 Münster, Germany.

Solvey Pollmann (S)

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, Interdisciplinary Fabry Center (IFAZ), University Hospital Münster, 48149 Münster, Germany.

Veerle Van Marck (V)

Gerhard-Domagk-Institute of Pathology, University Hospital Münster, 48149 Münster, Germany.

Thomas Weide (T)

Department of Medicine D, Division of General Internal and Emergency Medicine, Nephrology, and Rheumatology, University Hospital Münster, 48149 Münster, Germany.

Hermann Pavenstädt (H)

Department of Medicine D, Division of General Internal and Emergency Medicine, Nephrology, and Rheumatology, University Hospital Münster, 48149 Münster, Germany.

Eva Brand (E)

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, Interdisciplinary Fabry Center (IFAZ), University Hospital Münster, 48149 Münster, Germany.

Malte Lenders (M)

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, Interdisciplinary Fabry Center (IFAZ), University Hospital Münster, 48149 Münster, Germany.

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Classifications MeSH