Intramuscular Exposure to a Lethal Dose of Ricin Toxin Leads to Endothelial Glycocalyx Shedding and Microvascular Flow Abnormality in Mice and Swine.
Animals
Antigens, CD
/ genetics
Cadherins
/ genetics
Dose-Response Relationship, Drug
Endothelial Cells
/ cytology
Female
Gene Expression
/ drug effects
Glycocalyx
/ chemistry
Heparitin Sulfate
/ chemistry
Humans
Hyaluronic Acid
/ chemistry
Hydrolysis
Injections, Intramuscular
Kidney
/ drug effects
Liver
/ drug effects
Mice
Microcirculation
/ drug effects
Ricin
/ isolation & purification
Ricinus
/ chemistry
Spleen
/ drug effects
Swine
Syndecan-1
/ chemistry
Vascular Endothelial Growth Factor A
/ genetics
glycocalyx shedding
heparan sulfate
hyaluronic acid
intramuscular
microcirculation
ricin
syndecan-1
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
16 Nov 2021
16 Nov 2021
Historique:
received:
12
10
2021
revised:
09
11
2021
accepted:
15
11
2021
entrez:
27
11
2021
pubmed:
28
11
2021
medline:
17
12
2021
Statut:
epublish
Résumé
Ricin toxin isolated from the castor bean (
Identifiants
pubmed: 34830227
pii: ijms222212345
doi: 10.3390/ijms222212345
pmc: PMC8618821
pii:
doi:
Substances chimiques
Antigens, CD
0
Cadherins
0
Sdc1 protein, mouse
0
Syndecan-1
0
Vascular Endothelial Growth Factor A
0
cadherin 5
0
vascular endothelial growth factor A, mouse
0
Hyaluronic Acid
9004-61-9
Ricin
9009-86-3
Heparitin Sulfate
9050-30-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
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