Decreased reward-related brain function prospectively predicts increased substance use.


Journal

Journal of abnormal psychology
ISSN: 1939-1846
Titre abrégé: J Abnorm Psychol
Pays: United States
ID NLM: 0034461

Informations de publication

Date de publication:
Nov 2021
Historique:
entrez: 29 11 2021
pubmed: 30 11 2021
medline: 15 12 2021
Statut: ppublish

Résumé

Substance use and addiction are prominent global health concerns and are associated with abnormalities in reward sensitivity. Reward sensitivity and approach motivation are supported by a fronto-striatal neural circuit including the orbitofrontal cortex (OFC), ventral striatum (VS), and dorsal striatum (DS). Although research highlights abnormalities in reward neural circuitry among individuals with problematic substance use, questions remain about whether such use arises from excessively high, or excessively low, reward sensitivity. This study examined whether reward-related brain function predicted subsequent substance use course. Participants were 79 right-handed individuals (

Identifiants

pubmed: 34843292
pii: 2022-06920-006
doi: 10.1037/abn0000711
pmc: PMC8634780
mid: NIHMS1738251
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

886-898

Subventions

Organisme : NIMH NIH HHS
ID : T32 MH126368
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH077908
Pays : United States
Organisme : Civic Foundation
Organisme : NIMH NIH HHS
ID : R01 MH126911
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH123473
Pays : United States

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Auteurs

Corinne P Bart (CP)

Department of Psychology, Temple University.

Robin Nusslock (R)

Department of Psychology, Northwestern University.

Tommy H Ng (TH)

Department of Psychology, Temple University.

Madison K Titone (MK)

Department of Psychology, Temple University.

Ann L Carroll (AL)

Department of Psychology, Northwestern University.

Katherine S F Damme (KSF)

Department of Psychology, Northwestern University.

Christina B Young (CB)

Department of Psychiatry and Behavioral Sciences, Stanford University.

Casey C Armstrong (CC)

Department of Psychology, Northwestern University.

Jason Chein (J)

Department of Psychology, Temple University.

Lauren B Alloy (LB)

Department of Psychology, Temple University.

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Classifications MeSH