Gut-brain mechanisms underlying changes in disordered eating behaviour after bariatric surgery: a review.
Bariatric surgery
Disordered eating
Gut-brain axis
Obesity
Reward
Taste preferences
Journal
Reviews in endocrine & metabolic disorders
ISSN: 1573-2606
Titre abrégé: Rev Endocr Metab Disord
Pays: Germany
ID NLM: 100940588
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
accepted:
12
11
2021
pubmed:
2
12
2021
medline:
27
7
2022
entrez:
1
12
2021
Statut:
ppublish
Résumé
Bariatric surgery results in long-term weight loss and an improved metabolic phenotype due to changes in the gut-brain axis regulating appetite and glycaemia. Neuroendocrine alterations associated with bariatric surgery may also influence hedonic aspects of eating by inducing changes in taste preferences and central reward reactivity towards palatable food. However, the impact of bariatric surgery on disordered eating behaviours (e.g.: binge eating, loss-of-control eating, emotional eating and 'addictive eating'), which are commonly present in people with obesity are not well understood. Increasing evidence suggests gut-derived signals, such as appetitive hormones, bile acid profiles, microbiota concentrations and associated neuromodulatory metabolites, can influence pathways in the brain implicated in food intake, including brain areas involved in sensorimotor, reward-motivational, emotional-arousal and executive control components of food intake. As disordered eating prevalence is a key mediator of weight-loss success and patient well-being after bariatric surgery, understanding how changes in the gut-brain axis contribute to disordered eating incidence and severity after bariatric surgery is crucial to better improve treatment outcomes in people with obesity.
Identifiants
pubmed: 34851508
doi: 10.1007/s11154-021-09696-4
pii: 10.1007/s11154-021-09696-4
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
733-751Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Références
The GBD 2015 Obesity Collaborators. Health Effects of Overweight and Obesity in 195 Countries over 25 Years. 2017. https://doi.org/10.1056/NEJMoa1614362 .
Sjöström L, et al. Bariatric surgery and long-term cardiovascular events. JAMA. 2012;307:56–65.
pubmed: 22215166
doi: 10.1001/jama.2011.1914
Griffiths LJ, Parsons TJ, Hill AJ. Self-esteem and quality of life in obese children and adolescents: A systematic review. Int J Pediatr Obes. 2010;5:282–304.
pubmed: 20210677
doi: 10.3109/17477160903473697
Wu Y-K, Berry DC. Impact of weight stigma on physiological and psychological health outcomes for overweight and obese adults: A systematic review. J Adv Nurs. 2018;74:1030–42.
pubmed: 29171076
doi: 10.1111/jan.13511
Williams G, Fruhbeck G. Obesity: Science to practice. John Wiley & Sons; 2009.
Succurro E, et al. Obese patients with a binge eating disorder have an unfavorable metabolic and inflammatory profile. Medicine (Baltimore). 2015;94.
Saunders R. Binge eating in gastric bypass patients before surgery. Obes Surg. 1999;9:72–6.
pubmed: 10065590
doi: 10.1381/096089299765553845
Mannucci E, et al. Quality of life and overweight: the obesity related well-being (Orwell 97) questionnaire. Addict Behav. 1999;24(3):345–57.
pubmed: 10400274
doi: 10.1016/S0306-4603(98)00055-0
Sjöström L, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351:2683–93.
pubmed: 15616203
doi: 10.1056/NEJMoa035622
Rogers AM. Current state of bariatric surgery: Procedures, data, and patient management. Tech Vasc Interv Radiol. 2020;23:100654.
pubmed: 32192634
doi: 10.1016/j.tvir.2020.100654
Ramos A, et al. IFSO Fifth Global Registry Report. Dendrite & Clinical Systems. 2019; 1-100.
Manning S, Pucci A, Batterham RL. Roux-en-Y gastric bypass: Effects on feeding behavior and underlying mechanisms. J Clin Invest. 2015;125:939–48.
pubmed: 25729850
pmcid: 4362264
doi: 10.1172/JCI76305
Mulla CM, Middelbeek RJW, Patti M-E. Mechanisms of weight loss and improved metabolism following bariatric surgery. Ann N Y Acad Sci. 2018;1411:53–64.
pubmed: 28868615
doi: 10.1111/nyas.13409
Miras AD, le Roux CW. Mechanisms underlying weight loss after bariatric surgery. Nat Rev Gastroenterol Hepatol. 2013;10:575–84.
pubmed: 23835488
doi: 10.1038/nrgastro.2013.119
Murphy KG, Bloom SR. Gut hormones and the regulation of energy homeostasis. Nature. 2006;444:854–9.
pubmed: 17167473
doi: 10.1038/nature05484
Al-Najim W, Docherty NG, le Roux CW. Food intake and eating behavior after bariatric surgery. Physiol Rev. 2018;98:1113–41.
pubmed: 29717927
doi: 10.1152/physrev.00021.2017
Opozda M, Chur-Hansen A, Wittert G. Changes in problematic and disordered eating after gastric bypass, adjustable gastric banding and vertical sleeve gastrectomy: A systematic review of pre-post studies. Obes Rev. 2016;17:770–92.
pubmed: 27296934
doi: 10.1111/obr.12425
Vainik U, García-García I, Dagher A. Uncontrolled eating: A unifying heritable trait linked with obesity, overeating, personality and the brain. Eur J Neurosci. 2019;50:2430–45.
pubmed: 30667547
doi: 10.1111/ejn.14352
Stammers L, et al. Identifying stress-related eating in behavioural research: A review. Horm Behav. 2020;124:104752.
pubmed: 32305343
doi: 10.1016/j.yhbeh.2020.104752
Dingemans A, Danner U, Parks M. Emotion regulation in binge eating disorder: A review. Nutrients. 2017;9:1274.
pmcid: 5707746
doi: 10.3390/nu9111274
van Strien T. Causes of emotional eating and matched treatment of obesity. Curr Diab Rep. 2018;18:35.
pubmed: 29696418
pmcid: 5918520
doi: 10.1007/s11892-018-1000-x
Kessler RM, Hutson PH, Herman BK, Potenza MN. The neurobiological basis of binge-eating disorder. Neurosci Biobehav Rev. 2016;63:223–38.
pubmed: 26850211
doi: 10.1016/j.neubiorev.2016.01.013
Parker K, O’Brien P, Brennan L. Measurement of disordered eating following bariatric surgery: A systematic review of the literature. Obes Surg. 2014;24:945–53.
pubmed: 24744189
doi: 10.1007/s11695-014-1248-4
Baldofski S, et al. Nonnormative eating behavior and psychopathology in prebariatric patients with binge-eating disorder and night eating syndrome. Surg Obes Relat Dis. 2015;11:621–6.
pubmed: 25887494
doi: 10.1016/j.soard.2014.09.018
Spirou D, Raman J, Smith E. Psychological outcomes following surgical and endoscopic bariatric procedures: A systematic review. Obes Rev. 2020;21.
Ivezaj V, Wiedemann AA, Grilo CM. Food addiction and bariatric surgery: A systematic review of the literature: Food addiction and bariatric surgery. Obes Rev. 2017;18:1386–97.
pubmed: 28948684
pmcid: 5691599
doi: 10.1111/obr.12600
Dodsworth A, Warren-Forward H, Baines S. Changes in eating behavior after laparoscopic adjustable gastric banding: A systematic review of the literature. Obes Surg. 2010;20:1579–93.
pubmed: 20820936
doi: 10.1007/s11695-010-0270-4
Wong LY, et al. Change in emotional eating after bariatric surgery: Systematic review and meta-analysis. BJS Open. 2020;4:995–1014.
pmcid: 7709382
doi: 10.1002/bjs5.50318
Athanasiadis DI, Martin A, Kapsampelis P, Monfared S, Stefanidis D. Factors associated with weight regain post-bariatric surgery: A systematic review. Surg Endosc. 2021. https://doi.org/10.1007/s00464-021-08329-w .
doi: 10.1007/s00464-021-08329-w
pubmed: 33988770
Bryant EJ, Malik MS, Whitford-Bartle T, Waters GM. The effects of bariatric surgery on psychological aspects of eating behaviour and food intake in humans. Appetite. 2020;150:104575.
pubmed: 31875518
doi: 10.1016/j.appet.2019.104575
Pepino MY, Stein RI, Eagon JC, Klein S. Bariatric surgery-induced weight loss causes remission of food addiction in extreme obesity. Obesity. 2014;22:1792–8.
pubmed: 24852693
doi: 10.1002/oby.20797
Clark SM, Saules KK. Validation of the Yale Food Addiction Scale among a weight-loss surgery population. Eat Behav. 2013;14:216–9.
pubmed: 23557824
doi: 10.1016/j.eatbeh.2013.01.002
Kofman MD, Lent MR, Swencionis C. Maladaptive eating patterns, quality of life, and weight outcomes following gastric bypass: Results of an Internet survey. Obesity. 2010;18:1938–43.
pubmed: 20168309
doi: 10.1038/oby.2010.27
Smith KE, et al. Loss of control eating and binge eating in the 7 years following bariatric surgery. Obes Surg. 2019;29:1773–80.
pubmed: 30820886
pmcid: 6948918
doi: 10.1007/s11695-019-03791-x
Conceição EM, Utzinger LM, Pisetsky EM. Eating disorders and problematic eating behaviours before and after bariatric surgery: Characterization, assessment and association with treatment outcomes. Eur Eat Disord Rev. 2015;23:417–25.
pubmed: 26315343
pmcid: 4861632
doi: 10.1002/erv.2397
Marino JM, et al. The emergence of eating pathology after bariatric surgery: A rare outcome with important clinical implications. Int J Eat Disord. 2012;45:179–84.
pubmed: 21495051
doi: 10.1002/eat.20891
Colles SL, Dixon JB, O’Brien PE. Grazing and loss of control related to eating: Two high-risk factors following bariatric surgery. Obesity. 2008;16:615–22.
pubmed: 18239603
doi: 10.1038/oby.2007.101
Herpertz S, et al. Does obesity surgery improve psychosocial functioning? A systematic review. Int J Obes. 2003;27:1300–14.
doi: 10.1038/sj.ijo.0802410
Powers PS, Perez A, Boyd F, Rosemurgy A. Eating pathology before and after bariatric surgery: A prospective study. Int J Eat Disord. 1999;25:293–300.
pubmed: 10191994
doi: 10.1002/(SICI)1098-108X(199904)25:3<293::AID-EAT7>3.0.CO;2-G
Busetto L, et al. Weight loss and postoperative complications in morbidly obese patients with binge eating disorder treated by laparoscopic adjustable gastric banding. Obes Surg. 2005;15:195–201.
pubmed: 15802061
doi: 10.1381/0960892053268327
Saunders R. Compulsive eating and gastric bypass surgery: What does hunger have to do with It? Obes Surg. 2001;11:757–61.
pubmed: 11775577
doi: 10.1381/09608920160558731
Williams-Kerver GA, Steffen KJ, Mitchell JE. Eating pathology after bariatric surgery: An updated review of the recent literature. Curr Psychiatry Rep. 2019;21:86.
pubmed: 31410596
pmcid: 7953688
doi: 10.1007/s11920-019-1071-7
Rolls ET. Taste, olfactory and food texture reward processing in the brain and the control of appetite. Proc Nutr Soc. 2012;71:488–501.
pubmed: 22989943
doi: 10.1017/S0029665112000821
Oberndorfer TA, et al. Altered insula response to sweet taste processing after recovery from anorexia and bulimia nervosa. Am J Psychiatry. 2013;170:1143–51.
pubmed: 23732817
pmcid: 3971875
doi: 10.1176/appi.ajp.2013.11111745
Radeloff D, et al. High-fat taste challenge reveals altered striatal response in women recovered from bulimia nervosa: A pilot study. World J Biol Psychiatry. 2014;15:307–16.
pubmed: 22540408
doi: 10.3109/15622975.2012.671958
Kenler HA, Brolin RE, Cody RP. Changes in eating behavior after horizontal gastroplasty and Roux-en-Y gastric bypass. Am J Clin Nutr. 1990;52:87–92.
pubmed: 2360554
doi: 10.1093/ajcn/52.1.87
Olbers T, et al. Body composition, dietary intake, and energy expenditure after laparoscopic Roux-en-Y gastric bypass and laparoscopic vertical banded gastroplasty. Ann Surg. 2006;244:715–22.
pubmed: 17060764
pmcid: 1856598
doi: 10.1097/01.sla.0000218085.25902.f8
Ernst B, Thurnheer M, Wilms B, Schultes B. Differential changes in dietary habits after gastric bypass versus gastric banding operations. Obes Surg. 2009;19:274–80.
pubmed: 19034589
doi: 10.1007/s11695-008-9769-3
Zerrweck C, et al. Taste and olfactory changes following laparoscopic gastric bypass and sleeve gastrectomy. Obes Surg. 2016;26:1296–302.
pubmed: 26475030
doi: 10.1007/s11695-015-1944-8
Gero D, et al. Desire for core tastes decreases after sleeve gastrectomy: A single-center longitudinal observational study with 6-month follow-up. Obes Surg. 2017;27:2919–26.
pubmed: 28560529
doi: 10.1007/s11695-017-2718-2
Scholtz S, et al. Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding. Gut. 2014;63:891–902.
pubmed: 23964100
doi: 10.1136/gutjnl-2013-305008
Duan S, et al. Bariatric surgery induces alterations in effective connectivity between the orbitofrontal cortex and limbic regions in obese patients. Sci China Inf Sci. 2020;63:170104.
doi: 10.1007/s11432-019-2817-x
le Roux CW, et al. Gastric bypass reduces fat intake and preference. Am J Physiol Regul Integr Comp Physiol. 2011;301:R1057–66.
pubmed: 21734019
pmcid: 3197335
doi: 10.1152/ajpregu.00139.2011
Seyfried F, et al. Effects of preoperative exposure to a high-fat versus a low-fat diet on ingestive behavior after gastric bypass surgery in rats. Surg Endosc. 2013;27:4192–201.
pubmed: 23719976
pmcid: 3824302
doi: 10.1007/s00464-013-3020-6
Zheng H, et al. Meal patterns, satiety, and food choice in a rat model of Roux-en-Y gastric bypass surgery. Am J Physiol Regul Integr Comp Physiol. 2009;297:R1273–82.
pubmed: 19726714
pmcid: 2777767
doi: 10.1152/ajpregu.00343.2009
Shin AC, Zheng H, Pistell PJ, Berthoud H-R. Roux-en-Y gastric bypass surgery changes food reward in rats. Int J Obes. 2011;2005(35):642–51.
doi: 10.1038/ijo.2010.174
Saeidi N, et al. Sleeve gastrectomy and Roux-en-Y gastric bypass exhibit differential effects on food preferences, nutrient absorption and energy expenditure in obese rats. Int J Obes. 2012;2005(36):1396–402.
doi: 10.1038/ijo.2012.167
Bueter M, et al. Alterations of sucrose preference after Roux-en-Y gastric bypass. Physiol Behav. 2011;104:709–21.
pubmed: 21827777
doi: 10.1016/j.physbeh.2011.07.025
Chelikani PK, Shah IH, Taqi E, Sigalet DL, Koopmans HH. Comparison of the effects of Roux-en-Y gastric bypass and ileal transposition surgeries on food intake, body weight, and circulating peptide YY concentrations in rats. Obes Surg. 2010;20:1281–8.
pubmed: 20386999
doi: 10.1007/s11695-010-0139-6
Wilson-Pérez HE, et al. The effect of vertical sleeve gastrectomy on food choice in rats. Int J Obes. 2013;2005(37):288–95.
doi: 10.1038/ijo.2012.18
García-Cabrerizo R, Carbia C, O’Riordan KJ, Schellekens H, Cryan JF. Microbiota-gut-brain axis as a regulator of reward processes. J Neurochem. 2021;157:1495–524.
pubmed: 33368280
doi: 10.1111/jnc.15284
Volkow ND, Wang G-J, Baler RD. Reward, dopamine and the control of food intake: Implications for obesity. Trends Cogn Sci. 2011;15:37–46.
pubmed: 21109477
doi: 10.1016/j.tics.2010.11.001
Dallman MF, et al. Chronic stress and obesity: A new view of “comfort food.” Proc Natl Acad Sci U S A. 2003;100:11696–701.
pubmed: 12975524
pmcid: 208820
doi: 10.1073/pnas.1934666100
Meule A. The psychology of food cravings: The role of food deprivation. Curr Nutr Rep. 2020;9:251–7.
pubmed: 32578025
pmcid: 7399671
doi: 10.1007/s13668-020-00326-0
Burge JC, Schaumburg JZ, Choban PS, DiSilvestro RA, Flancbaum L. Changes in patients’ taste acuity after Roux-en-Y gastric bypass for clinically severe obesity. J Am Diet Assoc. 1995;95:666–70.
pubmed: 7759742
doi: 10.1016/S0002-8223(95)00182-4
Altun H, et al. Improved gustatory sensitivity in morbidly obese patients after laparoscopic sleeve gastrectomy. Ann Otol Rhinol Laryngol. 2016;125:536–40.
pubmed: 26848035
doi: 10.1177/0003489416629162
El Labban S, Safadi B, Olabi A. Effect of Roux-en-Y gastric bypass and sleeve gastrectomy on taste acuity and sweetness acceptability in postsurgical subjects. Nutrition. 2016;32:1299–302.
pubmed: 27264159
doi: 10.1016/j.nut.2016.03.022
Pepino MY, et al. Changes in taste perception and eating behavior after bariatric surgery-induced weight loss in women. Obesity. 2014;22:E13–20.
pubmed: 24167016
doi: 10.1002/oby.20649
Smith KR, et al. Taste-related reward is associated with weight loss following bariatric surgery. J Clin Invest. 2020;130:4370–81.
pubmed: 32427584
pmcid: 7410047
Thanos PK, et al. Roux-en-Y gastric bypass alters brain activity in regions that underlie reward and taste perception. PLoS One. 2015;10:e0125570.
pubmed: 26039080
pmcid: 4454506
doi: 10.1371/journal.pone.0125570
Hajnal A, et al. Gastric bypass surgery alters behavioral and neural taste functions for sweet taste in obese rats. Am J Physiol Gastrointest Liver Physiol. 2010;299:G967–79.
pubmed: 20634436
pmcid: 2957340
doi: 10.1152/ajpgi.00070.2010
Korner J, et al. Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY, and insulin. J Clin Endocrinol Metab. 2005;90:359–65.
pubmed: 15483088
doi: 10.1210/jc.2004-1076
le Roux CW, et al. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg. 2007;246:780–5.
pubmed: 17968169
doi: 10.1097/SLA.0b013e3180caa3e3
Dickson SL, et al. The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: A new role for mesolimbic GLP-1 receptors. J Neurosci. 2012;32:4812–20.
pubmed: 22492036
pmcid: 6620919
doi: 10.1523/JNEUROSCI.6326-11.2012
Hankir MK, et al. Gastric bypass surgery recruits a gut PPAR-α-striatal D1R pathway to reduce fat appetite in obese rats. Cell Metab. 2017;25:335–44.
pubmed: 28065827
doi: 10.1016/j.cmet.2016.12.006
Tellez LA, et al. A gut lipid messenger links excess dietary fat to dopamine deficiency. Science. 2013;341:800–2.
pubmed: 23950538
doi: 10.1126/science.1239275
Romano A, et al. Oleoylethanolamide decreases frustration stress-induced binge-like eating in female rats: A novel potential treatment for binge eating disorder. Neuropsychopharmacology. 2020. https://doi.org/10.1038/s41386-020-0686-z .
doi: 10.1038/s41386-020-0686-z
pubmed: 32353860
pmcid: 7609309
Hankir MK, et al. Suppressed fat appetite after Roux-en-Y gastric bypass surgery associates with reduced brain μ-opioid receptor availability in diet-induced obese male rats. Front Neurosci. 2017;10:620.
pubmed: 28133443
pmcid: 5233681
doi: 10.3389/fnins.2016.00620
Laleh P, Yaser K, Alireza O. Oleoylethanolamide: A novel pharmaceutical agent in the management of obesity-an updated review. J Cell Physiol. 2019;234:7893–902.
pubmed: 30537148
doi: 10.1002/jcp.27913
Karimian Azari E, et al. Vagal afferents are not necessary for the satiety effect of the gut lipid messenger oleoylethanolamide. Am J Physiol-Regul Integr Comp Physiol. 2014;307:R167–78.
doi: 10.1152/ajpregu.00067.2014
Hutch CR, et al. Oea signaling pathways and the metabolic benefits of vertical sleeve gastrectomy. Ann Surg. 2020;271:509–18.
pubmed: 30702457
doi: 10.1097/SLA.0000000000003093
Goldstein N, et al. Hypothalamic detection of macronutrients via multiple gut-brain pathways. Cell Metab. 2021;33:676-687.e5.
pubmed: 33450178
pmcid: 7933100
doi: 10.1016/j.cmet.2020.12.018
Nielsen MS, Schmidt JB, le Roux CW, Sjödin A. Effects of Roux-en-Y Gastric bypass and sleeve gastrectomy on food preferences and potential mechanisms involved. Curr Obes Rep. 2019;8:292–300.
pubmed: 31222526
doi: 10.1007/s13679-019-00354-0
Seeley RJ, et al. The role of CNS glucagon-like peptide-1 (7–36) amide receptors in mediating the visceral illness effects of lithium chloride. J Neurosci. 2000;20:1616–21.
pubmed: 10662851
pmcid: 6772354
doi: 10.1523/JNEUROSCI.20-04-01616.2000
Dischinger U, et al. GLP-1 and PYY3-36 reduce high-fat food preference additively after Roux-en-Y gastric bypass in diet-induced obese rats. Surg Obes Relat Dis. 2019;15:1483–92.
pubmed: 31548004
doi: 10.1016/j.soard.2019.04.008
Ahmad N, Pfalzer A, Kaplan L. Roux-en-Y gastric bypass normalizes the blunted postprandial bile acid excursion associated with obesity. Int J Obes. 2013;2005(37):1553–9.
doi: 10.1038/ijo.2013.38
Deems RO, Friedman MI. Macronutrient selection in an animal model of cholestatic liver disease. Appetite. 1988;11:73–80.
pubmed: 3239965
doi: 10.1016/S0195-6663(88)80007-2
Perino A, et al. Central anorexigenic actions of bile acids are mediated by TGR5. Nat Metab. 2021;3:595–603.
pubmed: 34031591
pmcid: 7610881
doi: 10.1038/s42255-021-00398-4
Castellanos-Jankiewicz A, et al. Hypothalamic bile acid-TGR5 signaling protects from obesity. Cell Metab. 2021;33:1483-1492.e10.
pubmed: 33887197
doi: 10.1016/j.cmet.2021.04.009
Bensalem A, et al. Bile acid receptor TGR5 is critically involved in preference for dietary lipids and obesity. J Nutr Biochem. 2020;76:108298.
pubmed: 31812910
doi: 10.1016/j.jnutbio.2019.108298
Nielsen MS, et al. Factors associated with favorable changes in food preferences after bariatric surgery. Obes Surg. 2021;31:3514–24.
pubmed: 33786744
doi: 10.1007/s11695-021-05374-1
Heitmann BL, Lissner L. Dietary underreporting by obese individuals–is it specific or non-specific? BMJ. 1995;311:986–9.
pubmed: 7580640
pmcid: 2550989
doi: 10.1136/bmj.311.7011.986
Nielsen MS, et al. Bariatric surgery does not affect food preferences, but individual changes in food preferences may predict weight loss. Obesity. 2018;26:1879–87.
doi: 10.1002/oby.22272
Frank S, et al. Altered brain activity in severely obese women may recover after Roux-en Y gastric bypass surgery. Int J Obes. 2014;38:341–8.
doi: 10.1038/ijo.2013.60
Ochner CN, et al. Selective reduction in neural responses to high calorie foods following gastric bypass surgery. Ann Surg. 2011;253:502–7.
pubmed: 21169809
doi: 10.1097/SLA.0b013e318203a289
Ochner CN, et al. Neural responsivity to food cues in fasted and fed states pre and post gastric bypass surgery. Neurosci Res. 2012;74:138–43.
pubmed: 22921709
pmcid: 3626459
doi: 10.1016/j.neures.2012.08.002
Gupta A, Osadchiy V, Mayer EA. Brain–gut–microbiome interactions in obesity and food addiction. Nat Rev Gastroenterol Hepatol. 2020;17:655–72.
pubmed: 32855515
pmcid: 7841622
doi: 10.1038/s41575-020-0341-5
Ravichandran S, et al. Alterations in reward network functional connectivity are associated with increased food addiction in obese individuals. Sci Rep. 2021;11:1–15.
doi: 10.1038/s41598-020-79139-8
Weygandt M, Schaefer A, Schienle A, Haynes J-D. Diagnosing different binge-eating disorders based on reward-related brain activation patterns. Hum Brain Mapp. 2012. https://doi.org/10.1002/hbm.21345 .
doi: 10.1002/hbm.21345
pubmed: 22887826
van Bloemendaal L, et al. Brain reward-system activation in response to anticipation and consumption of palatable food is altered by glucagon-like peptide-1 receptor activation in humans. Diabetes Obes Metab. 2015;17:878–86.
pubmed: 26094857
doi: 10.1111/dom.12506
van Bloemendaal L, et al. Emotional eating is associated with increased brain responses to food-cues and reduced sensitivity to GLP-1 receptor activation. Obesity. 2015;23:2075–82.
pubmed: 26331843
doi: 10.1002/oby.21200
Wood SMW, et al. Emotional eating and routine restraint scores are associated with activity in brain regions involved in urge and self-control. Physiol Behav. 2016;165:405–12.
pubmed: 27575974
pmcid: 5036966
doi: 10.1016/j.physbeh.2016.08.024
Chechlacz M, et al. Diabetes dietary management alters responses to food pictures in brain regions associated with motivation and emotion: A functional magnetic resonance imaging study. Diabetologia. 2009;52:524–33.
pubmed: 19139843
doi: 10.1007/s00125-008-1253-z
Killgore WDS, Yurgelun-Todd DA. Affect modulates appetite-related brain activity to images of food. Int J Eat Disord. 2006;39:357–63.
pubmed: 16565998
doi: 10.1002/eat.20240
Wagner DD, Boswell RG, Kelley WM, Heatherton TF. Inducing negative affect increases the reward value of appetizing foods in dieters. J Cogn Neurosci. 2012. https://doi.org/10.1162/jocn_a_00238 .
doi: 10.1162/jocn_a_00238
pubmed: 23163418
pmcid: 3848029
Eiler WJA, Dzemidzic M, Case KR, Considine RV, Kareken DA. Correlation between ventromedial prefrontal cortex activation to food aromas and cue-driven eating: An fMRI study. Chemosens Percept. 2012;5:27–36.
pubmed: 25485031
pmcid: 4255712
doi: 10.1007/s12078-011-9112-6
Bohon C, Stice E. Negative affect and neural response to palatable food intake in bulimia nervosa. Appetite. 2012;58:964–70.
pubmed: 22387716
pmcid: 3589569
doi: 10.1016/j.appet.2012.02.051
Thanarajah SE, et al. Food intake recruits orosensory and post-ingestive dopaminergic circuits to affect eating desire in humans. Cell Metab. 2019;29:695-706.e4.
pubmed: 30595479
doi: 10.1016/j.cmet.2018.12.006
Dunn JP, et al. Decreased dopamine type 2 receptor availability after bariatric surgery: Preliminary findings. Brain Res. 2010;1350:123–30.
pubmed: 20362560
pmcid: 2926260
doi: 10.1016/j.brainres.2010.03.064
Steele KE, et al. Alterations of central dopamine receptors before and after gastric bypass surgery. Obes Surg. 2010;20:369–74.
pubmed: 19902317
doi: 10.1007/s11695-009-0015-4
Hankir MK, Ashrafian H, Hesse S, Horstmann A, Fenske WK. Distinctive striatal dopamine signaling after dieting and gastric bypass. Trends Endocrinol Metab. 2015;26:223–30.
pubmed: 25887491
doi: 10.1016/j.tem.2015.03.005
Reddy IA, et al. Striatal dopamine homeostasis is altered in mice following Roux-en-Y gastric bypass surgery. ACS Chem Neurosci. 2014;5:943–51.
pubmed: 25068716
doi: 10.1021/cn500137d
van der Zwaal EM, et al. Striatal dopamine D2/3 receptor availability increases after long-term bariatric surgery-induced weight loss. Eur Neuropsychopharmacol. 2016;26:1190–200.
pubmed: 27184782
doi: 10.1016/j.euroneuro.2016.04.009
Han W, et al. Striatal dopamine links gastrointestinal rerouting to altered sweet appetite. Cell Metab. 2016;23:103–12.
pubmed: 26698915
doi: 10.1016/j.cmet.2015.10.009
Goldstone AP, et al. Link between increased satiety gut hormones and reduced food reward after gastric bypass surgery for obesity. J Clin Endocrinol Metab. 2016;101:599–609.
pubmed: 26580235
doi: 10.1210/jc.2015-2665
ten Kulve JS, et al. Endogenous GLP1 and GLP1 analogue alter CNS responses to palatable food consumption. J Endocrinol. 2016;229:1–12.
pubmed: 26769912
doi: 10.1530/JOE-15-0461
Sweeney P, Yang Y. Neural circuit mechanisms underlying emotional regulation of homeostatic feeding. Trends Endocrinol Metab. 2017;28:437–48.
pubmed: 28279562
pmcid: 5438765
doi: 10.1016/j.tem.2017.02.006
Bartra O, McGuire JT, Kable JW. The valuation system: A coordinate-based meta-analysis of BOLD fMRI experiments examining neural correlates of subjective value. Neuroimage. 2013;76:412–27.
pubmed: 23507394
doi: 10.1016/j.neuroimage.2013.02.063
Frost G, et al. The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism. Nat Commun. 2014;5:3611.
pubmed: 24781306
doi: 10.1038/ncomms4611
Byrne CS, et al. Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods. Am J Clin Nutr. 2016;104:5–14.
pubmed: 27169834
pmcid: 4919527
doi: 10.3945/ajcn.115.126706
Chambers ES, et al. Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults. Gut. 2015;64:1744–54.
pubmed: 25500202
doi: 10.1136/gutjnl-2014-307913
Torres-Fuentes C, et al. Short-chain fatty acids and microbiota metabolites attenuate ghrelin receptor signaling. FASEB J. 2019;33:13546–59.
pubmed: 31545915
doi: 10.1096/fj.201901433R
Dong TS, et al. A distinct brain-gut-microbiome profile exists for females with obesity and food addiction. Obesity. 2020;28:1477–86.
pubmed: 32935533
doi: 10.1002/oby.22870
Sanmiguel CP, et al. Surgically induced changes in gut microbiome and hedonic eating as related to weight loss: Preliminary findings in obese women undergoing bariatric surgery. Psychosom Med. 2017;79:880–7.
pubmed: 28570438
pmcid: 5628115
doi: 10.1097/PSY.0000000000000494
Dong TS, et al. Improvement in uncontrolled eating behavior after laparoscopic sleeve gastrectomy is associated with alterations in the brain–gut–microbiome axis in obese women. Nutrients. 2020;12(10):2924.
pmcid: 7599899
doi: 10.3390/nu12102924
Hong J, et al. Reversal of functional brain activity related to gut microbiome and hormones after VSG surgery in patients with obesity. J Clin Endocrinol Metab. 2021. https://doi.org/10.1210/clinem/dgab297 .
doi: 10.1210/clinem/dgab297
pubmed: 34302730
pmcid: 8372652
Herman A, Bajaka A. The role of the intestinal microbiota in eating disorders – bulimia nervosa and binge eating disorder. Psychiatry Res. 2021;300:113923.
pubmed: 33857846
doi: 10.1016/j.psychres.2021.113923
Jennis M, et al. Microbiota-derived tryptophan indoles increase after gastric bypass surgery and reduce intestinal permeability in vitro and in vivo. Neurogastroenterol Motil. 2018;30:e13178.
doi: 10.1111/nmo.13178
Osadchiy V, et al. Correlation of tryptophan metabolites with connectivity of extended central reward network in healthy subjects. PLoS One. 2018;13(8):e0201772.
pubmed: 30080865
pmcid: 6078307
doi: 10.1371/journal.pone.0201772
Yano JM, et al. Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell. 2015;161:264–76.
pubmed: 25860609
pmcid: 4393509
doi: 10.1016/j.cell.2015.02.047
Finch L & Tomiyama AJ. Stress-induced eating dampens physiological and behavioral stress responses. In Nutrition in the prevention and treatment of abdominal obesity. 2019. Ch. 18; p. 189–195. https://doi.org/10.1016/B978-0-12-816093-0.00015-X .
van Strien T, et al. Emotional eating and food intake after sadness and joy. Appetite. 2013;66:20–5.
pubmed: 23470231
doi: 10.1016/j.appet.2013.02.016
Tryon MS, Carter CS, DeCant R, Laugero KD. Chronic stress exposure may affect the brain’s response to high calorie food cues and predispose to obesogenic eating habits. Physiol Behav. 2013;120:233–42.
pubmed: 23954410
doi: 10.1016/j.physbeh.2013.08.010
Wingenfeld K, et al. Stress reactivity and its effects on subsequent food intake in depressed and healthy women with and without adverse childhood experiences. Psychoneuroendocrinology. 2017;80:122–30.
pubmed: 28324701
doi: 10.1016/j.psyneuen.2017.03.014
Gluck ME, Geliebter A, Hung J, Yahav E. Cortisol, hunger, and desire to binge eat following a cold stress test in obese women with binge eating disorder. Psychosom Med. 2004;66:876–81.
pubmed: 15564352
doi: 10.1097/01.psy.0000143637.63508.47
Tomiyama AJ, Dallman MF, Epel ES. Comfort food is comforting to those most stressed: Evidence of the chronic stress response network in high stress women. Psychoneuroendocrinology. 2011;36:1513–9.
pubmed: 21906885
pmcid: 3425607
doi: 10.1016/j.psyneuen.2011.04.005
Dietrich A, Hollmann M, Mathar D, Villringer A, Horstmann A. Brain regulation of food craving: Relationships with weight status and eating behavior. Int J Obes. 2016;40:982–9.
doi: 10.1038/ijo.2016.28
García-García I, et al. Reward processing in obesity, substance addiction and non-substance addiction. Obes Rev. 2014;15:853–69.
pubmed: 25263466
doi: 10.1111/obr.12221
Higgs S, Spetter MS. Cognitive control of eating: The role of memory in appetite and weight gain. Curr Obes Rep. 2018;7:50–9.
pubmed: 29430616
pmcid: 5829122
doi: 10.1007/s13679-018-0296-9
Demos KE, Heatherton TF, Kelley WM. Individual differences in nucleus accumbens activity to food and sexual images predict weight gain and sexual behavior. J Neurosci. 2012;32:5549–52.
pubmed: 22514316
pmcid: 3377379
doi: 10.1523/JNEUROSCI.5958-11.2012
Hankir MK, et al. Homeostatic, reward and executive brain functions after gastric bypass surgery. Appetite. 2020;146:104419.
pubmed: 31472199
doi: 10.1016/j.appet.2019.104419
Hankir MK, Seyfried F, Miras AD, Cowley MA. Brain feeding circuits after Roux-en-Y gastric bypass. Trends Endocrinol Metab. 2018;29:218–37.
pubmed: 29475578
doi: 10.1016/j.tem.2018.01.009
Smitka K, et al. Current aspects of the role of autoantibodies directed against appetite-regulating hormones and the gut microbiome in eating disorders. Front Endocrinol. 2021;12:293.
doi: 10.3389/fendo.2021.613983
Skonieczna-Żydecka K, et al. Gut Biofactory—Neurocompetent Metabolites within the Gastrointestinal Tract. A Scoping Review. Nutrients. 2020;12(11):3369.
pmcid: 7693392
doi: 10.3390/nu12113369
Tavares GA, et al. Early weaning leads to disruption of homeostatic and hedonic eating behaviors and modulates serotonin (5HT) and dopamine (DA) systems in male adult rats. Behav Brain Res. 2020;383:112531.
pubmed: 32014554
doi: 10.1016/j.bbr.2020.112531
Haahr ME, et al. Central 5-HT neurotransmission modulates weight loss following gastric bypass surgery in obese individuals. J Neurosci. 2015;35:5884–9.
pubmed: 25855196
pmcid: 6605315
doi: 10.1523/JNEUROSCI.3348-14.2015
Leyrolle Q, et al. Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients. Clin Nutr. 2021;40:2035–44.
pubmed: 33023763
doi: 10.1016/j.clnu.2020.09.025
Clarke G, et al. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol Psychiatry. 2013;18:666–73.
pubmed: 22688187
doi: 10.1038/mp.2012.77
Rea K, Dinan TG, Cryan JF. The microbiome: A key regulator of stress and neuroinflammation. Neurobiol Stress. 2016;4:23–33.
pubmed: 27981187
pmcid: 5146205
doi: 10.1016/j.ynstr.2016.03.001
Navarro-Tapia E, et al. Effects of microbiota imbalance in anxiety and eating disorders: Probiotics as novel therapeutic approaches. Int J Mol Sci. 2021;22:2351.
pubmed: 33652962
pmcid: 7956573
doi: 10.3390/ijms22052351
Yang Y, Shields GS, Guo C, Liu Y. Executive function performance in obesity and overweight individuals: A meta-analysis and review. Neurosci Biobehav Rev. 2018;84:225–44.
pubmed: 29203421
doi: 10.1016/j.neubiorev.2017.11.020
Monica D, et al. Assessment of executive functions in obese individuals with binge eating disorder. Braz J Psychiatry. 2010;32:381–8.
doi: 10.1590/S1516-44462010000400011
Manasse SM, et al. Executive functioning in overweight individuals with and without loss-of-control eating. Eur Eat Disord Rev. 2014;22:373–7.
pubmed: 24962637
pmcid: 4133293
doi: 10.1002/erv.2304
Han JE, Boachie N, Garcia-Garcia I, Michaud A, Dagher A. Neural correlates of dietary self-control in healthy adults: A meta-analysis of functional brain imaging studies. Physiol Behav. 2018;192:98–108.
pubmed: 29496487
doi: 10.1016/j.physbeh.2018.02.037
Lavagnino L, Arnone D, Cao B, Soares JC, Selvaraj S. Inhibitory control in obesity and binge eating disorder: A systematic review and meta-analysis of neurocognitive and neuroimaging studies. Neurosci Biobehav Rev. 2016;68:714–26.
pubmed: 27381956
doi: 10.1016/j.neubiorev.2016.06.041
Balodis IM, Grilo CM, Potenza MN. Neurobiological features of binge eating disorder. CNS Spectr. 2015;20:557–65.
pubmed: 26530404
pmcid: 4658223
doi: 10.1017/S1092852915000814
Hege MA, et al. Attentional impulsivity in binge eating disorder modulates response inhibition performance and frontal brain networks. Int J Obes. 2015;2005(39):353–60.
doi: 10.1038/ijo.2014.99
Burger KS, Stice E. Relation of dietary restraint scores to activation of reward-related brain regions in response to food intake, anticipated intake, and food pictures. Neuroimage. 2011;55:233–9.
pubmed: 21147234
doi: 10.1016/j.neuroimage.2010.12.009
Coletta M, et al. Brain activation in restrained and unrestrained eaters: An fMRI study. J Abnorm Psychol. 2009;118:598–609.
pubmed: 19685956
doi: 10.1037/a0016201
DelParigi A, et al. Successful dieters have increased neural activity in cortical areas involved in the control of behavior. Int J Obes. 2007;31:440–8.
doi: 10.1038/sj.ijo.0803431
Hollmann M, et al. Neural correlates of the volitional regulation of the desire for food. Int J Obes. 2012;36:648–55.
doi: 10.1038/ijo.2011.125
Born JM, et al. Differences between liking and wanting signals in the human brain and relations with cognitive dietary restraint and body mass index. Am J Clin Nutr. 2011;94:392–403.
pubmed: 21653801
doi: 10.3945/ajcn.111.012161
Demos KE, Kelley WM, Heatherton TF. Dietary restraint violations influence reward responses in nucleus accumbens and amygdala. J Cogn Neurosci. 2011;23:1952–63.
pubmed: 20807052
doi: 10.1162/jocn.2010.21568
Zoon HFA, et al. Altered neural inhibition responses to food cues after Roux-en-Y Gastric Bypass. Biol Psychol. 2018;137:34–41.
pubmed: 29944963
doi: 10.1016/j.biopsycho.2018.06.005
Goldman RL, et al. Executive control circuitry differentiates degree of success in weight loss following gastric-bypass surgery. Obesity. 2013;21:2189–96.
pubmed: 24136926
doi: 10.1002/oby.20575
Hu Y. Laparoscopic sleeve gastrectomy improves brain connectivity in obese patients. J Neurol. 2020;10.
Weygandt M, et al. Interactions between neural decision-making circuits predict long-term dietary treatment success in obesity. Neuroimage. 2019;184:520–34.
pubmed: 30253206
doi: 10.1016/j.neuroimage.2018.09.058
Liu L, et al. Structural changes in brain regions involved in executive-control and self-referential processing after sleeve gastrectomy in obese patients. Brain Imaging Behav. 2019;13(3):830–40.
pubmed: 29948904
doi: 10.1007/s11682-018-9904-2
Hu Y, et al. Brain connectivity, and hormonal and behavioral correlates of sustained weight loss in obese patients after laparoscopic sleeve gastrectomy. Cereb Cortex. 2021;31:1284–95.
pubmed: 33037819
doi: 10.1093/cercor/bhaa294
Prinz P, et al. Plasma bile acids show a positive correlation with body mass index and are negatively associated with cognitive restraint of eating in obese patients. Front Neurosci. 2015;9:199.
pubmed: 26089773
pmcid: 4452824
Delzenne NM, Cani PD, Daubioul C, Neyrinck AM. Impact of inulin and oligofructose on gastrointestinal peptides. Br J Nutr. 2005;93:S157–61.
pubmed: 15877889
doi: 10.1079/BJN20041342
Delbès A-S, et al. Prebiotics supplementation impact on the reinforcing and motivational aspect of feeding. Front Endocrinol. 2018;9:273.
doi: 10.3389/fendo.2018.00273
Association AP. Feeding and eating disorders: DSM-5® selections. American Psychiatric Pub; 2015.
Sarwer DB, Allison KC, Bailer BA, Faulconbridge LF. Psychosocial characteristics of bariatric surgery candidates. The ASMBS textbook of bariatric surgery: Volume 2: Integrated Health 2014. pp. 3–9.
Marek RJ, Ben-Porath YS, Ashton K, Heinberg LJ. Minnesota multiphasic personality inventory-2 restructured form (MMPI-2-RF) scale score differences in bariatric surgery candidates diagnosed with binge eating disorder versus BMI-matched controls. Int J Eat Disord. 2014;47:315–9.
pubmed: 24123190
doi: 10.1002/eat.22194
Mitchell JE, et al. Long-term follow-up of patients’ status after gastric bypass. Obes Surg. 2001;11:464–8.
pubmed: 11501356
doi: 10.1381/096089201321209341
Conceição EM, Goldschmidt A. Disordered eating after bariatric surgery: Clinical aspects, impact on outcomes, and intervention strategies. Curr Opin Psychiatry. 2019;32:504–9.
pubmed: 31343419
pmcid: 6768715
doi: 10.1097/YCO.0000000000000549
Niego SH, Kofman MD, Weiss JJ, Geliebter A. Binge eating in the bariatric surgery population: A review of the literature. Int J Eat Disord. 2007;40:349–59.
pubmed: 17304586
doi: 10.1002/eat.20376
White MA, Kalarchian MA, Masheb RM, Marcus MD, Grilo CM. Loss of control over eating predicts outcomes in bariatric surgery patients: A prospective, 24-month follow-up study. J Clin Psychiatry. 2009;70:0–0.
Saunders R. ‘Grazing’: A high-risk behavior. Obes Surg. 2004;14:98–102.
pubmed: 14980042
doi: 10.1381/096089204772787374
Lydecker JA, Ivezaj V, Grilo CM. Secretive eating and binge eating following bariatric surgery. Int J Eat Disord. 2019;52:935–40.
pubmed: 31033037
pmcid: 6687553
doi: 10.1002/eat.23089
Conceição EM, et al. Picking and nibbling: Frequency and associated clinical features in bulimia nervosa, anorexia nervosa and binge eating disorder. Int J Eat Disord. 2013;46:815–8.
pubmed: 23922133
pmcid: 4009470
doi: 10.1002/eat.22167
Conceição EM, et al. Stability of problematic eating behaviors and weight loss trajectories after bariatric surgery: A longitudinal observational study. Surg Obes Relat Dis. 2017;13:1063–70.
pubmed: 28209532
doi: 10.1016/j.soard.2016.12.006
Allison KC, et al. Night eating syndrome and binge eating disorder among persons seeking bariatric surgery: Prevalence and related features. Obesity. 2006;14:77S-82S.
pubmed: 16648598
doi: 10.1038/oby.2006.286
de Zwaan M, Marschollek M, Allison KC. The night eating syndrome (NES) in bariatric surgery patients. Eur Eat Disord Rev. 2015;23:426–34.
pubmed: 26395455
doi: 10.1002/erv.2405
Brode CS, Mitchell JE. Problematic eating behaviors and eating disorders associated with bariatric surgery. Psychiatr Clin North Am. 2019;42:287–97.
pubmed: 31046930
pmcid: 6501797
doi: 10.1016/j.psc.2019.01.014
Brown RM. Addiction-like synaptic impairments in diet-induced obesity. Biol. Psychiatry. 2015;81:797-806. https://doi.org/10.1016/j.biopsych.2015.11.019 .
Sevinçer GM. Food addiction and the outcome of bariatric surgery at 1-year: Prospective observational study. Psychiatry Res. 2016;6.