3D bioprinting of tissue units with mesenchymal stem cells, retaining their proliferative and differentiating potential, in polyphosphate-containing bio-ink.
bio-ink
biomineralization
bioprinting
mesenchymal stem cells
polyphosphate constituent
Journal
Biofabrication
ISSN: 1758-5090
Titre abrégé: Biofabrication
Pays: England
ID NLM: 101521964
Informations de publication
Date de publication:
31 12 2021
31 12 2021
Historique:
received:
09
09
2021
accepted:
01
12
2021
pubmed:
2
12
2021
medline:
16
4
2022
entrez:
1
12
2021
Statut:
epublish
Résumé
The three-dimensional (3D)-printing processes reach increasing recognition as important fabrication techniques to meet the growing demands in tissue engineering. However, it is imperative to fabricate 3D tissue units, which contain cells that have the property to be regeneratively active. In most bio-inks, a metabolic energy-providing component is missing. Here a formulation of a bio-ink is described, which is enriched with polyphosphate (polyP), a metabolic energy providing physiological polymer. The bio-ink composed of a scaffold (
Identifiants
pubmed: 34852334
doi: 10.1088/1758-5090/ac3f29
doi:
Substances chimiques
Polyphosphates
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Creative Commons Attribution license.