An immunodominant NP

Aged Amino Acid Sequence Antibodies, Viral / immunology Antibody Affinity / immunology COVID-19 / immunology Cell Line, Transformed Female Gene Expression Profiling HLA-B7 Antigen / immunology Humans Immunodominant Epitopes / immunology Immunologic Memory / immunology Male Middle Aged Nucleocapsid Proteins / immunology Receptors, Antigen, T-Cell / immunology SARS-CoV-2 / immunology Severity of Illness Index T-Lymphocytes, Cytotoxic / immunology Vaccinia virus / genetics

Journal

Nature immunology
ISSN: 1529-2916
Titre abrégé: Nat Immunol
Pays: United States
ID NLM: 100941354

Informations de publication

Date de publication:
01 2022
Historique:
received: 19 07 2021
accepted: 26 10 2021
pubmed: 3 12 2021
medline: 12 1 2022
entrez: 2 12 2021
Statut: ppublish

Résumé

NP

Identifiants

DOI: 10.1038/s41590-021-01084-z PMID: 34853448 PMC: PMC8709787
pubmed: 34853448
doi: 10.1038/s41590-021-01084-z
pii: 10.1038/s41590-021-01084-z
pmc: PMC8709787
mid: EMS137573
doi:

Substances chimiques

Antibodies, Viral 0
HLA-B*07:02 antigen 0
HLA-B7 Antigen 0
Immunodominant Epitopes 0
Nucleocapsid Proteins 0
Receptors, Antigen, T-Cell 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

50-61

Subventions

Organisme : Medical Research Council
ID : MR/M00919X/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_20002
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 200838/Z/16/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 204969/Z/16/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 201488/Z/16/Z
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/V028502/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0501329
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Versus Arthritis
ID : 22252
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_00008/11
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_00008/5
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/L018942/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0600520
Pays : United Kingdom
Organisme : Medical Research Council
ID : G1001046
Pays : United Kingdom

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2021. The Author(s).

Références

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Auteurs

Yanchun Peng (Y)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
ORCID: 0000-0003-2340-0499

Suet Ling Felce (SL)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Danning Dong (D)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
CAMS Key Laboratory of Tumor Immunology and Radiation Therapy, Xinjiang Tumor Hospital, Xinjiang Medical University, Urumqi, China.

Frank Penkava (F)

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
ORCID: 0000-0001-9163-8576

Alexander J Mentzer (AJ)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0002-4502-2209

Xuan Yao (X)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Guihai Liu (G)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Beijing You'an Hospital, Capital Medical University, Beijing, China.

Zixi Yin (Z)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0002-2044-5838

Ji-Li Chen (JL)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.

Yongxu Lu (Y)

Department of Pathology, University of Cambridge, Cambridge, UK.

Dannielle Wellington (D)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.

Peter A C Wing (PAC)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0002-2354-3281

Delaney C C Dominey-Foy (DCC)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Chen Jin (C)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Wenbo Wang (W)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Megat Abd Hamid (MA)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Ricardo A Fernandes (RA)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Beibei Wang (B)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Anastasia Fries (A)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0003-1609-5991

Xiaodong Zhuang (X)

Nuffield Department of Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0002-6870-9003

Neil Ashley (N)

Single Cell Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Timothy Rostron (T)

Sequencing Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Craig Waugh (C)

Flow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Paul Sopp (P)

Flow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Philip Hublitz (P)

Genome Engineering Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0001-8810-3247

Ryan Beveridge (R)

Virus Screening Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Tiong Kit Tan (TK)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0001-8746-8308

Christina Dold (C)

Oxford Vaccine Group, Department of Paediatrics, and NIHR Oxford Biomedical Research Centre, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.

Andrew J Kwok (AJ)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0001-8928-5054

Charlotte Rich-Griffin (C)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
ORCID: 0000-0001-8212-9542

Wanwisa Dejnirattisa (W)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Chang Liu (C)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Prathiba Kurupati (P)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

Isar Nassiri (I)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Department of Oncology, University of Oxford, Oxford, UK.
MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Robert A Watson (RA)

Department of Oncology, University of Oxford, Oxford, UK.
MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Orion Tong (O)

Department of Oncology, University of Oxford, Oxford, UK.
MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0002-0659-5944

Chelsea A Taylor (CA)

Department of Oncology, University of Oxford, Oxford, UK.
MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Piyush Kumar Sharma (P)

Department of Oncology, University of Oxford, Oxford, UK.
MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0002-6247-3503

Bo Sun (B)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
ORCID: 0000-0002-5507-6657

Fabiola Curion (F)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Helmholtz Center Munich-German Research Center for Environmental Health, Institute of Computational Biology, Neuherberg, Germany.

Santiago Revale (S)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.

Lucy C Garner (LC)

MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0002-6461-252X

Kathrin Jansen (K)

Kennedy Institute for Rheumatology, University of Oxford, Oxford, UK.
ORCID: 0000-0002-3803-7680

Ricardo C Ferreira (RC)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.

Moustafa Attar (M)

Kennedy Institute for Rheumatology, University of Oxford, Oxford, UK.
ORCID: 0000-0003-4116-1276

Jeremy W Fry (JW)

ProImmune Limited, Oxford, UK.
ORCID: 0000-0003-3689-6606

Rebecca A Russell (RA)

Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
ORCID: 0000-0002-6517-6483

Hans J Stauss (HJ)

Institute of Immunity and Transplantation, University College London, London, UK.
ORCID: 0000-0003-4340-7911

William James (W)

James & Lillian Martin Centre, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
ORCID: 0000-0002-2506-1198

Alain Townsend (A)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.

Ling-Pei Ho (LP)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

Paul Klenerman (P)

Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
ORCID: 0000-0003-4307-9161

Juthathip Mongkolsapaya (J)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Dengue Hemorrhagic Fever Research Unit, Office for Research and Development, Faculty of Medicine, Siriaj Hospital, Mahidol Unviversity, Bangkok, Thailand.
ORCID: 0000-0003-3416-9480

Gavin R Screaton (GR)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
ORCID: 0000-0002-3549-4309

Calliope Dendrou (C)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.

Stephen N Sansom (SN)

Kennedy Institute for Rheumatology, University of Oxford, Oxford, UK.
ORCID: 0000-0003-4569-8513

Rachael Bashford-Rogers (R)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
ORCID: 0000-0002-6838-0711

Benny Chain (B)

Division of Infection and Immunity, University College London, London, UK.
ORCID: 0000-0002-7417-3970

Geoffrey L Smith (GL)

Department of Pathology, University of Cambridge, Cambridge, UK.
ORCID: 0000-0002-3730-9955

Jane A McKeating (JA)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Benjamin P Fairfax (BP)

Department of Oncology, University of Oxford, Oxford, UK.
MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Paul Bowness (P)

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
ORCID: 0000-0003-4597-0484

Andrew J McMichael (AJ)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Graham Ogg (G)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.

Julian C Knight (JC)

Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK. julian.knight@well.ox.ac.uk.
Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK. julian.knight@well.ox.ac.uk.
Nuffield Department of Medicine, University of Oxford, Oxford, UK. julian.knight@well.ox.ac.uk.

Tao Dong (T)

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. tao.dong@imm.ox.ac.uk.
Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK. tao.dong@imm.ox.ac.uk.
Nuffield Department of Medicine, University of Oxford, Oxford, UK. tao.dong@imm.ox.ac.uk.
ORCID: 0000-0003-3545-3758

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › An immunodominant NP
questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › An immunodominant NP
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps antiviraux › An immunodominant NP
questionsmedicales.fr › Phénomènes du système immunitaire › Réaction antigène-anticorps › Affinité des anticorps › An immunodominant NP
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › An immunodominant NP
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Lignée de cellules transformées › An immunodominant NP
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes › An immunodominant NP
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes HLA › Antigènes HLA-B › Antigène HLA-B7 › An immunodominant NP
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › An immunodominant NP
questionsmedicales.fr › Facteurs biologiques › Antigènes › Épitopes › Épitopes immunodominants › An immunodominant NP
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Mémoire immunologique › An immunodominant NP
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › An immunodominant NP
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales structurales › Protéines nucléocapside › An immunodominant NP
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux antigènes › Récepteurs aux antigènes des cellules T › An immunodominant NP
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Nidovirales › Coronaviridae › Coronavirus › Betacoronavirus › Virus du SRAS › SARS-CoV-2 › An immunodominant NP
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