Changes in carbon dioxide production and oxygen uptake evaluated using indirect calorimetry in mechanically ventilated patients with sepsis.
Carbon dioxide production
Indirect calorimetry
Lactate
Oxygen extraction
Sepsis
Journal
Critical care (London, England)
ISSN: 1466-609X
Titre abrégé: Crit Care
Pays: England
ID NLM: 9801902
Informations de publication
Date de publication:
04 12 2021
04 12 2021
Historique:
received:
19
09
2021
accepted:
17
11
2021
entrez:
5
12
2021
pubmed:
6
12
2021
medline:
31
12
2021
Statut:
epublish
Résumé
Several clinical guidelines recommend monitoring blood lactate levels and central venous oxygen saturation for hemodynamic management of patients with sepsis. We hypothesized that carbon dioxide production (VCO Adult patients with sepsis who required mechanical ventilation in the intensive care unit (ICU) of our hospital between September 2019 and March 2020 were prospectively enrolled. Sepsis was diagnosed according to Sepsis-3. Continuous measurement of VCO Thirty-four patients with sepsis were enrolled, 26 of whom survived 76%. Significant differences in the slope of VCO The non-survivors in this study showed temporal decreases in both VCO
Sections du résumé
BACKGROUND
Several clinical guidelines recommend monitoring blood lactate levels and central venous oxygen saturation for hemodynamic management of patients with sepsis. We hypothesized that carbon dioxide production (VCO
METHODS
Adult patients with sepsis who required mechanical ventilation in the intensive care unit (ICU) of our hospital between September 2019 and March 2020 were prospectively enrolled. Sepsis was diagnosed according to Sepsis-3. Continuous measurement of VCO
RESULTS
Thirty-four patients with sepsis were enrolled, 26 of whom survived 76%. Significant differences in the slope of VCO
CONCLUSIONS
The non-survivors in this study showed temporal decreases in both VCO
Identifiants
pubmed: 34863262
doi: 10.1186/s13054-021-03830-z
pii: 10.1186/s13054-021-03830-z
pmc: PMC8645073
doi:
Substances chimiques
Carbon Dioxide
142M471B3J
Lactic Acid
33X04XA5AT
Oxygen
S88TT14065
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
416Informations de copyright
© 2021. The Author(s).
Références
Clin Chest Med. 2016 Jun;37(2):321-31
pubmed: 27229648
JAMA. 2016 Feb 23;315(8):801-10
pubmed: 26903338
Respir Care. 2016 Mar;61(3):354-8
pubmed: 26715770
Shock. 2021 Jun 1;55(6):775-781
pubmed: 32881760
Crit Care. 2011 Jul 26;15(4):R176
pubmed: 21791065
Intensive Care Med. 2004 Dec;30(12):2170-9
pubmed: 15448891
Intensive Care Med. 2018 Jun;44(6):925-928
pubmed: 29675566
Ann Emerg Med. 2010 Jan;55(1):40-46.e1
pubmed: 19854541
Chest. 1992 Dec;102(6):1787-93
pubmed: 1446489
Resuscitation. 2018 Jun;127:89-94
pubmed: 29626611
J Crit Care. 2020 Apr;56:236-242
pubmed: 31982697
Mitochondrion. 2004 Sep;4(5-6):729-41
pubmed: 16120428
Lancet Respir Med. 2014 May;2(5):380-6
pubmed: 24740011
Intensive Care Med. 2017 Mar;43(3):304-377
pubmed: 28101605
Crit Care. 2011;15(5):R242
pubmed: 22014216
Crit Care Med. 2004 Aug;32(8):1637-42
pubmed: 15286537
Crit Care Clin. 2010 Apr;26(2):409-21, table of contents
pubmed: 20381729
Am J Respir Crit Care Med. 2010 Sep 15;182(6):752-61
pubmed: 20463176
J Am Heart Assoc. 2018 Jun 29;7(13):
pubmed: 29959138
Crit Care. 2002 Dec;6(6):491-9
pubmed: 12493070
Clin Nutr. 2015 Feb;34(1):60-5
pubmed: 24485773
Crit Care Clin. 2011 Apr;27(2):299-326
pubmed: 21440203
Clin Nutr. 2013 Feb;32(1):118-21
pubmed: 22763268
JAMA. 2009 Dec 2;302(21):2323-9
pubmed: 19952319
Crit Care. 2020 Aug 31;24(1):535
pubmed: 32867825
Mayo Clin Proc. 2013 Oct;88(10):1127-40
pubmed: 24079682
N Engl J Med. 1994 Jun 16;330(24):1717-22
pubmed: 7993413