Relation of Liver Volume to Adverse Cardiovascular Events in Adolescents and Adults With Fontan Circulation.
Adolescent
Adult
Central Venous Pressure
Elasticity Imaging Techniques
Female
Fontan Procedure
Heart Defects, Congenital
/ surgery
Heart Failure
/ epidemiology
Heart Transplantation
/ statistics & numerical data
Heart-Assist Devices
/ statistics & numerical data
Hepatomegaly
/ diagnostic imaging
Hospitalization
Humans
Liver
/ diagnostic imaging
Magnetic Resonance Imaging
Male
Mortality
Organ Size
Proportional Hazards Models
Young Adult
Journal
The American journal of cardiology
ISSN: 1879-1913
Titre abrégé: Am J Cardiol
Pays: United States
ID NLM: 0207277
Informations de publication
Date de publication:
15 02 2022
15 02 2022
Historique:
received:
12
08
2021
revised:
14
10
2021
accepted:
19
10
2021
pubmed:
12
12
2021
medline:
1
2
2022
entrez:
11
12
2021
Statut:
ppublish
Résumé
Elevated central venous pressure in those with Fontan circulation causes liver congestion and hepatomegaly. We assessed if liver volume by magnetic resonance imaging (MRI) is associated with adverse cardiovascular outcomes. Retrospective study of 122 patients with Fontan circulation who were >10 years old and had a liver MRI with magnetic resonance elastography. Liver volume (ml) was measured by manual segmentation from axial T2-weighted images and was indexed to body surface area. The composite outcome included death, heart transplant, ventricular assist device placement, or nonelective cardiovascular hospitalization. The median age at the time of MRI was 18.9 (interquartile range 15.8 to 25.9) years, and 47% of the patients were women. The mean indexed liver volume was 1,133 ± 180 ml/m
Identifiants
pubmed: 34893302
pii: S0002-9149(21)01107-3
doi: 10.1016/j.amjcard.2021.10.045
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
88-94Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosures The authors have no conflicts of interest to declare.