Epitope Mapping of an Anti-CD20 Monoclonal Antibody (C

C20Mab-60 CD20 enzyme-linked immunosorbent assay epitope mapping monoclonal antibody

Journal

Monoclonal antibodies in immunodiagnosis and immunotherapy
ISSN: 2167-9436
Titre abrégé: Monoclon Antib Immunodiagn Immunother
Pays: United States
ID NLM: 101590955

Informations de publication

Date de publication:
Dec 2021
Historique:
entrez: 27 12 2021
pubmed: 28 12 2021
medline: 14 1 2022
Statut: ppublish

Résumé

CD20 is a glycosylated transmembrane protein and is expressed on normal B cells and B cell malignancies. Therapeutic antibodies against CD20 are developed and used in clinic. The understanding of antibody-antigen binding by revealing the epitope is essential for future application to antibody technology. Previously, we developed an anti-human CD20 monoclonal antibody, C

Identifiants

pubmed: 34958272
doi: 10.1089/mab.2021.0042
doi:

Substances chimiques

Antibodies, Monoclonal 0
Antigens, CD20 0
Epitopes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

250-254

Auteurs

Junko Takei (J)

Department of Antibody Drug Development and Tohoku University Graduate School of Medicine, Sendai, Japan.

Hiroyuki Suzuki (H)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Teizo Asano (T)

Department of Antibody Drug Development and Tohoku University Graduate School of Medicine, Sendai, Japan.

Guanjie Li (G)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Masaki Saito (M)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Mika K Kaneko (MK)

Department of Antibody Drug Development and Tohoku University Graduate School of Medicine, Sendai, Japan.

Yukinari Kato (Y)

Department of Antibody Drug Development and Tohoku University Graduate School of Medicine, Sendai, Japan.
Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

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Classifications MeSH