A previously unappreciated polymorphism in the beta chain of I-A

Alleles Amino Acid Sequence Animals Antibodies, Monoclonal / metabolism Antigen-Presenting Cells / metabolism Autoimmunity CD4-Positive T-Lymphocytes / immunology Female Histocompatibility Antigens Class II / chemistry Hydrogen Bonding Mice Molecular Dynamics Simulation Peptides / chemistry Polymorphism, Genetic Protein Multimerization Protein Stability Protein Structure, Secondary
Autoimmunity CD4 T cells MHC class Il structure Polymorphism

Journal

Molecular immunology
ISSN: 1872-9142
Titre abrégé: Mol Immunol
Pays: England
ID NLM: 7905289

Informations de publication

Date de publication:
03 2022
Historique:
received: 01 10 2021
revised: 13 12 2021
accepted: 26 12 2021
pubmed: 8 1 2022
medline: 3 3 2022
entrez: 7 1 2022
Statut: ppublish

Résumé

In the process of structure-function studies on the MHC class II molecule expressed in autoimmunity prone SJL mice, I-A

Identifiants

DOI: 10.1016/j.molimm.2021.12.022 PMID: 34995990 PMC: PMC9261112
pubmed: 34995990
pii: S0161-5890(21)00371-0
doi: 10.1016/j.molimm.2021.12.022
pmc: PMC9261112
mid: NIHMS1768881
pii:
doi:

Substances chimiques

Antibodies, Monoclonal 0
Histocompatibility Antigens Class II 0
Peptides 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

17-26

Subventions

Organisme : NIAID NIH HHS
ID : HHSN272201400005C
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM118166
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002529
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

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Auteurs

Katherine A Richards (KA)

David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave, Box 609, Rochester, NY 14642, United States.

Courtney Lavery (C)

David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave, Box 609, Rochester, NY 14642, United States.

Grant L J Keller (GLJ)

Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, IN 46556, United States.

Jim Miller (J)

David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave, Box 609, Rochester, NY 14642, United States.

Brian M Baker (BM)

Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, IN 46556, United States.

Andrea J Sant (AJ)

David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave, Box 609, Rochester, NY 14642, United States. Electronic address: andrea_sant@urmc.rochester.edu.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Allèles › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Eucaryotes › Animaux › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Cellules présentatrices d'antigène › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Auto-immunité › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Lymphocytes T CD4+ › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes d'histocompatibilité de classe II › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Phénomènes chimiques › Liaison hydrogène › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Polymorphisme génétique › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Multimérisation de protéines › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Stabilité protéique › A previously unappreciated polymorphism in the...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure secondaire des protéines › A previously unappreciated polymorphism in the...