Spectral imaging with dual-layer spectral detector computed tomography for the detection of perfusion defects in acute coronary syndrome.
Acute coronary syndrome
Dual-energy scanned projection
Multidetector computed tomography
Myocardial perfusion
Journal
Heart and vessels
ISSN: 1615-2573
Titre abrégé: Heart Vessels
Pays: Japan
ID NLM: 8511258
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
received:
13
09
2021
accepted:
24
12
2021
pubmed:
11
1
2022
medline:
1
6
2022
entrez:
10
1
2022
Statut:
ppublish
Résumé
To evaluate the feasibility of spectral imaging with dual-layer spectral detector computed tomography (CT) for the diagnosis of acute coronary syndrome. We identified 30 consecutive patients who underwent cardiac CT using dual-layer spectral detector CT and were diagnosed with acute ischemic syndrome by an invasive coronary angiography. We reconstructed 120 kVp images and generated virtual monochromatic images (VMIs; 40-200 keV in 10 keV increments), iodine concentration maps, and effective atomic number (Z) maps. We calculated the contrast and contrast-to-noise ratio (CNR) between myocardial normal and hypo-perfusion and chose the VMIs with the best CNR for quantitative analysis. We compared the image noise, contrast, and CNR of 120 kVp images and the best VMIs, CT value, iodine concentration, and effective Z between myocardial normal and hypo-perfusion with the paired t test. As the X-ray energy decreased, venous attenuation, contrast, and CNR gradually increased. The 40 keV image yielded the best CNR. The contrast and CNR between myocardial normal and hypo-perfusion were significantly higher in 40 keV images than those in 120 kVp images. The iodine concentration and the effective Z were significantly higher in normal myocardium than those in hypo-perfused myocardium. Spectral imaging with dual-layer spectral detector CT is a feasible technique to detect the hypo-perfused area of acute ischemic syndrome.
Identifiants
pubmed: 35006370
doi: 10.1007/s00380-021-02019-2
pii: 10.1007/s00380-021-02019-2
doi:
Substances chimiques
Iodine
9679TC07X4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1115-1124Informations de copyright
© 2022. Springer Japan KK, part of Springer Nature.
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