Understanding the relative contributions of prematurity and congenital anomalies to neonatal mortality.
Journal
Journal of perinatology : official journal of the California Perinatal Association
ISSN: 1476-5543
Titre abrégé: J Perinatol
Pays: United States
ID NLM: 8501884
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
received:
16
08
2021
accepted:
07
12
2021
revised:
17
11
2021
pubmed:
17
1
2022
medline:
14
5
2022
entrez:
16
1
2022
Statut:
ppublish
Résumé
To examine the relative contributions of preterm delivery and congenital anomalies to neonatal mortality. Retrospective analysis of 2009-2011 linked birth cohort-hospital discharge files for California, Missouri, Pennsylvania and South Carolina. Deaths were classified by gestational age and three definitions of congenital anomaly: any ICD-9 code for an anomaly, any anomaly with a significant mortality risk, and anomalies recorded on the death certificate. In total, 59% of the deaths had an ICD-9 code for an anomaly, only 43% had a potentially fatal anomaly, and only 34% had a death certificate anomaly. Preterm infants (<37 weeks GA) accounted for 80% of deaths; those preterm infants without a potentially fatal anomaly diagnosis comprised 53% of all neonatal deaths. The share of preterm deaths with a potentially fatal anomaly decreases with GA. Congenital anomalies are responsible for about 40% of neonatal deaths while preterm without anomalies are responsible for over 50%.
Identifiants
pubmed: 35034095
doi: 10.1038/s41372-021-01298-x
pii: 10.1038/s41372-021-01298-x
pmc: PMC9098660
mid: NIHMS1762930
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
569-573Subventions
Organisme : NICHD NIH HHS
ID : R01 HD084819
Pays : United States
Informations de copyright
© 2021. This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.
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