The effect of prophylactic use of tranexamic acid for cesarean section.
Tranexamic acid
cesarean section
hemoglobin
post-partum hemorrhage
prophylaxis
renal failure
Journal
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
ISSN: 1476-4954
Titre abrégé: J Matern Fetal Neonatal Med
Pays: England
ID NLM: 101136916
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
pubmed:
25
1
2022
medline:
24
11
2022
entrez:
24
1
2022
Statut:
ppublish
Résumé
Treatment with tranexamic acid (TxA) significantly reduces maternal death due to postpartum hemorrhage. There is increasing interest in whether it can also be used as prophylaxis for postpartum hemorrhage, especially during cesarean sections (CS). This impact study is aimed to determine the effect of routine prophylactic tranexamic acid during CS on maternal hemorrhage and the rate of the associated side effects. This retrospective population-based cohort single-center impact study include 2000 women who delivered by CS divided into two groups with ( Women who did not receive TxA prophylactic had a higher rate of >10% hemoglobin decrease and a higher rate of ≥2 g/dL hemoglobin decrease Than those who received TxA prophylaxis ( The finding of our study suggest that prophylactic administration of TxA prior to CS improves maternal and neonatal outcomes.
Identifiants
pubmed: 35068314
doi: 10.1080/14767058.2021.2019215
doi:
Substances chimiques
Tranexamic Acid
6T84R30KC1
Antifibrinolytic Agents
0
Hemoglobins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM