Basal Cells in the Epidermis and Epidermal Differentiation.
Basal cells in the epidermis
Basal keratinocytes
Epidermal differentiation
Epidermal stem cells
Epidermis
Hair follicle
Hair follicle stem cells
LGR5
LGR6
Lrig1
Stochastic epidermis
Wnt signaling
Journal
Stem cell reviews and reports
ISSN: 2629-3277
Titre abrégé: Stem Cell Rev Rep
Pays: United States
ID NLM: 101752767
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
accepted:
27
08
2021
pubmed:
27
1
2022
medline:
24
8
2022
entrez:
26
1
2022
Statut:
ppublish
Résumé
A definite identification of epidermal stem cells is not known and the mechanism of epidermal differentiation is not fully understood. Toward both of these quests, considerable information is available from the research on lineage tracing and clonal growth analysis in the basal layer of the epidermis, on the hair follicle and the interfollicular epidermal stem cells, and on Wnt signaling along with its role in the developmental patterning and cell differentiation. In this paper, literature on the aforementioned research has been collated and analyzed. In addition, models of the basal layer cellular composition and the epidermal differentiation have been presented. Graphical Abstract.
Identifiants
pubmed: 35080747
doi: 10.1007/s12015-021-10256-1
pii: 10.1007/s12015-021-10256-1
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1883-1891Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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