Ensuring the Sustainability of Biocatalysis.

biocatalysis enzyme stability product concentration productivity scale-up

Journal

ChemSusChem
ISSN: 1864-564X
Titre abrégé: ChemSusChem
Pays: Germany
ID NLM: 101319536

Informations de publication

Date de publication:
06 May 2022
Historique:
revised: 20 01 2022
received: 20 12 2021
pubmed: 28 1 2022
medline: 10 5 2022
entrez: 27 1 2022
Statut: ppublish

Résumé

Biocatalysis offers many attractive features for the synthetic chemist. In many cases, the high selectivity and ability to tailor specific enzyme features via protein engineering already make it the catalyst of choice. From the perspective of sustainability, several features such as catalysis under mild conditions and use of a renewable and biodegradable catalyst also look attractive. Nevertheless, to be sustainable at a larger scale it will be essential to develop processes operating at far higher concentrations of product, and which make better use of the enzyme via improved stability. In this Concept, it is argued that a particular emphasis on these specific metrics is of particular importance for the future implementation of biocatalysis in industry, at a level that fulfills its true potential.

Identifiants

pubmed: 35084801
doi: 10.1002/cssc.202102683
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202102683

Subventions

Organisme : European Research Council (ERC)
ID : 101021024

Informations de copyright

© 2022 Wiley-VCH GmbH.

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Auteurs

John M Woodley (JM)

Department of Chemical and Biochemical Engineering, Technical University of Denmark, 2800, Kgs Lyngby, Denmark.

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