Polygenic routes lead to parallel altitudinal adaptation in Heliosperma pusillum (Caryophyllaceae).
Heliosperma pusillum
RNA-seq
altitudinal adaptation
demography
ecotypes
parallel divergence
polygenic architecture
Journal
Molecular ecology
ISSN: 1365-294X
Titre abrégé: Mol Ecol
Pays: England
ID NLM: 9214478
Informations de publication
Date de publication:
04 2023
04 2023
Historique:
revised:
29
12
2021
received:
30
08
2021
accepted:
02
02
2022
medline:
12
4
2023
pubmed:
14
2
2022
entrez:
13
2
2022
Statut:
ppublish
Résumé
Understanding how organisms adapt to the environment is a major goal of modern biology. Parallel evolution-the independent evolution of similar phenotypes in different populations-provides a powerful framework to investigate the evolutionary potential of populations, the constraints of evolution, its repeatability and therefore its predictability. Here, we quantified the degree of gene expression and functional parallelism across replicated ecotype formation in Heliosperma pusillum (Caryophyllaceae), and gained insights into the architecture of adaptive traits. Population structure analyses and demographic modelling support a previously formulated hypothesis of parallel polytopic divergence of montane and alpine ecotypes. We detect a large proportion of differentially expressed genes (DEGs) underlying divergence within each replicate ecotype pair, with a strikingly low number of shared DEGs across pairs. Functional enrichment of DEGs reveals that the traits affected by significant expression divergence are largely consistent across ecotype pairs, in strong contrast to the nonshared genetic basis. The remarkable redundancy of differential gene expression indicates a polygenic architecture for the diverged adaptive traits. We conclude that polygenic traits appear key to opening multiple routes for adaptation, widening the adaptive potential of organisms.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1832-1847Subventions
Organisme : Austrian Science Fund FWF
ID : W 1225
Pays : Austria
Organisme : Austrian Science Fund FWF
ID : Y 661
Pays : Austria
Organisme : Austrian Science Fund
ID : W1225-B20
Organisme : Austrian Science Fund
ID : Y661-B16
Informations de copyright
© 2022 The Authors. Molecular Ecology published by John Wiley & Sons Ltd.
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