A Comprehensive Approach to Managing Methamphetamine-Associated Cardiomyopathy.


Journal

American journal of cardiovascular drugs : drugs, devices, and other interventions
ISSN: 1179-187X
Titre abrégé: Am J Cardiovasc Drugs
Pays: New Zealand
ID NLM: 100967755

Informations de publication

Date de publication:
Jul 2022
Historique:
accepted: 13 01 2022
pubmed: 15 2 2022
medline: 14 7 2022
entrez: 14 2 2022
Statut: ppublish

Résumé

Methamphetamines are illicit drugs of the amphetamine-type stimulant class that have been increasing in popularity, availability, and purity in recent decades. As a result, rates of methamphetamine-associated cardiomyopathy (MAC) are rising globally. MAC is associated with high rates of sudden cardiac arrest, late presentation, and poor outcomes. This review discusses the medical management of MAC, including anticipated challenges specific to methamphetamine users. Not only are patients with MAC more likely to present at a younger age and with multisystem disease than patients with cardiomyopathy of other etiologies, but there may also be significant behavioral, psychosocial, financial, and system-based challenges to providing the best medical care. An individualized treatment plan that emphasizes methamphetamine abstinence as the foundation of therapy, as well as introducing optimal heart failure therapy and providing multidisciplinary support is likely to result in optimal outcomes. Given the potential reversibility of MAC, institution of guideline-directed heart failure therapy and patient support for adherence to therapy and abstinence from methamphetamines should be energetically pursued.

Identifiants

pubmed: 35157254
doi: 10.1007/s40256-022-00523-y
pii: 10.1007/s40256-022-00523-y
doi:

Substances chimiques

Central Nervous System Stimulants 0
Methamphetamine 44RAL3456C

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

385-393

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.

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Auteurs

Michael Osekowski (M)

St Vincent's Hospital Melbourne, Fitzroy, VIC, 3065, Australia.

Adam Trytell (A)

St Vincent's Hospital Melbourne, Fitzroy, VIC, 3065, Australia.

Andre La Gerche (A)

St Vincent's Hospital Melbourne, Fitzroy, VIC, 3065, Australia.
National Centre for Sports Cardiology, Fitzroy, VIC, Australia.
Baker Heart and Diabetes Institute, Prahran, VIC, Australia.

David Prior (D)

St Vincent's Hospital Melbourne, Fitzroy, VIC, 3065, Australia.
National Centre for Sports Cardiology, Fitzroy, VIC, Australia.

Andrew MacIsaac (A)

St Vincent's Hospital Melbourne, Fitzroy, VIC, 3065, Australia.

Elizabeth D Paratz (ED)

St Vincent's Hospital Melbourne, Fitzroy, VIC, 3065, Australia. Elizabeth.paratz@svha.org.au.
Baker Heart and Diabetes Institute, Prahran, VIC, Australia. Elizabeth.paratz@svha.org.au.

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