Extracellular degradation of a polyurethane oligomer involving outer membrane vesicles and further insights on the degradation of 2,4-diaminotoluene in Pseudomonas capeferrum TDA1.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
17 02 2022
Historique:
received: 19 11 2021
accepted: 02 02 2022
entrez: 18 2 2022
pubmed: 19 2 2022
medline: 15 3 2022
Statut: epublish

Résumé

The continuing reports of plastic pollution in various ecosystems highlight the threat posed by the ever-increasing consumption of synthetic polymers. Therefore, Pseudomonas capeferrum TDA1, a strain recently isolated from a plastic dump site, was examined further regarding its ability to degrade polyurethane (PU) compounds. The previously reported degradation pathway for 2,4-toluene diamine, a precursor and degradation intermediate of PU, could be confirmed by RNA-seq in this organism. In addition, different cell fractions of cells grown on a PU oligomer were tested for extracellular hydrolytic activity using a standard assay. Strikingly, purified outer membrane vesicles (OMV) of P. capeferrum TDA1 grown on a PU oligomer showed higher esterase activity than cell pellets. Hydrolases in the OMV fraction possibly involved in extracellular PU degradation were identified by mass spectrometry. On this basis, we propose a model for extracellular degradation of polyester-based PUs by P. capeferrum TDA1 involving the role of OMVs in synthetic polymer degradation.

Identifiants

pubmed: 35177693
doi: 10.1038/s41598-022-06558-0
pii: 10.1038/s41598-022-06558-0
pmc: PMC8854710
doi:

Substances chimiques

Phenylenediamines 0
Polyurethanes 0
2,4-diaminotoluene IS1AKN4HYB

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2666

Informations de copyright

© 2022. The Author(s).

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Auteurs

Òscar Puiggené (Ò)

Department of Environmental Biotechnology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800, Kgs, Lyngby, Denmark.

María José Cárdenas Espinosa (MJC)

Department of Environmental Biotechnology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.

Dietmar Schlosser (D)

Department of Environmental Microbiology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.

Stephan Thies (S)

Institute of Molecular Enzyme Technology, Heinrich Heine University Dusseldorf, Jülich, Germany.

Nico Jehmlich (N)

Department Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.

Uwe Kappelmeyer (U)

Department of Environmental Biotechnology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.

Stephan Schreiber (S)

Department Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.

Daniel Wibberg (D)

Microbial Genomics and Biotechnology, Center for Biotechnology (CeBiTec), Bielefeld, Germany.

Joern Kalinowski (J)

Microbial Genomics and Biotechnology, Center for Biotechnology (CeBiTec), Bielefeld, Germany.

Hauke Harms (H)

Department of Environmental Microbiology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.

Hermann J Heipieper (HJ)

Department of Environmental Biotechnology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany. hermann.heipieper@ufz.de.

Christian Eberlein (C)

Department of Environmental Biotechnology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.

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