Versatile Near-Infrared Super-Resolution Imaging of Amyloid Fibrils with the Fluorogenic Probe CRANAD-2.
amyloid fibrils
curcumin derivatives
exchangeable fluorophore.
single-molecule localization microscopy
stimulated emission depletion microscopy
super-resolution imaging
transient binding
Journal
Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765
Titre abrégé: Chemistry
Pays: Germany
ID NLM: 9513783
Informations de publication
Date de publication:
01 Apr 2022
01 Apr 2022
Historique:
received:
04
01
2022
pubmed:
19
2
2022
medline:
6
4
2022
entrez:
18
2
2022
Statut:
ppublish
Résumé
CRANAD-2 is a fluorogenic curcumin derivative used for near-infrared detection and imaging in vivo of amyloid aggregates, which are involved in neurodegenerative diseases. We explore the performance of CRANAD-2 in two super-resolution imaging techniques, namely stimulated emission depletion (STED) and single-molecule localization microscopy (SMLM), with markedly different fluorophore requirements. By conveniently adapting the concentration of CRANAD-2, which transiently binds to amyloid fibrils, we show that it performs well in both techniques, achieving a resolution in the range of 45-55 nm. Correlation of SMLM with atomic force microscopy (AFM) validates the resolution of fine features in the reconstructed super-resolved image. The good performance and versatility of CRANAD-2 provides a powerful tool for near-infrared nanoscopic imaging of amyloids in vitro and in vivo.
Identifiants
pubmed: 35178798
doi: 10.1002/chem.202200026
doi:
Substances chimiques
Amyloid
0
Fluorescent Dyes
0
Curcumin
IT942ZTH98
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202200026Subventions
Organisme : Ministerio de Ciencia, Innovación y Universidades
ID : PCI2018-093064, PGC2018-094802-B-I00
Organisme : Ministerio de Ciencia, Innovación y Universidades
ID : SEV-2016-0686
Organisme : Comunidad de Madrid
ID : S2017/BMD-3867
Informations de copyright
© 2022 Wiley-VCH GmbH.
Références
F. Chiti, C. M. Dobson, Annu. Rev. Biochem. 2017, 86, 27-68.
P. A. Adlard, B. A. Tran, D. I. Finkelstein, P. M. Desmond, L. A. Johnston, A. I. Bush, G. F. Egan, Front. Neurol. Neurosci. 2014, 8, 327-349.
Z. Luo, H. Xu, L. Liu, T. Y. Ohulchanskyy, J. Qu, Biosensors 2021, 11, 255-273.
J. L. Jiménez, E. J. Nettleton, M. Bouchard, C. V. Robinson, C. M. Dobson, H. R. Saibil, Proc. Natl. Acad. Sci. USA 2002, 99, 9196-9201.
S. W. Hell, J. Wichmann, Opt. Lett. 1994, 19, 780-782.
E. Betzig, G. H. Patterson, R. Sougrat, O. W. Lindwasser, S. Olenych, J. S. Bonifacino, M. W. Davidson, J. Lippincott-Schwartz, H. F. Hess, Science 2006, 313, 1642-1645.
M. J. Rust, M. Bates, X. Zhuang, Nat. Methods 2006, 3, 793-795.
C. Werner, M. Sauer, C. Geis, Chem. Rev. 2021, 121, 11971-12015.
G. Vicidomini, P. Bianchini, A. Diaspro, Nat. Methods 2018, 15, 173-182.
M. Lelek, M. T. Gyparaki, G. Beliu, F. Schueder, J. Griffié, S. Manley, R. Jungmann, M. Sauer, M. Lakadamyali, C. Zimmer, Nat. Rev. Methods Primers 2021, 1, 39-65.
A. Aliyan, N. P. Cook, A. A. Martí, Chem. Rev. 2019, 119, 11819-11856.
C. F. Kaminski, G. S. Kaminski Schierle, Neurophotonics 2016, 3, 041807-041815.
M. Lu, C. F. Kaminski, G. S. Kaminski Schierle, Phys. Biol. 2020, 17, 021001-021013.
J. Torra, P. Bondia, S. Gutierrez-Erlandsson, B. Sot, C. Flors, Nanoscale 2020, 12, 15050-15053.
Z. Lv, L. Li, Z. Man, Z. Xu, H. Cui, R. Zhan, Q. He, L. Zheng, H. Fu, Nano Res. 2020, 13, 2556-2563.
H. A. Shaban, C. A. Valades-Cruz, J. Savatier, S. Brasselet, Sci. Rep. 2017, 7, 12482-12491.
K. Spehar, T. Ding, Y. Sun, N. Kedia, J. Lu, G. R. Nahass, M. D. Lew, J. Bieschke, ChemBioChem 2018, 19, 1944-1948.
J.-E. Lee, J. C. Sang, M. Rodrigues, A. R. Carr, M. H. Horrocks, S. De, M. N. Bongiovanni, P. Flagmeier, C. M. Dobson, D. J. Wales, S. F. Lee, D. Klenerman, Nano Lett. 2018, 18, 7494-7501.
L.-M. Needham, J. Weber, C. M. Pearson, D. T. Do, F. Gorka, G. Lyu, S. E. Bohndiek, T. N. Snaddon, S. F. Lee, J. Phys. Chem. Lett. 2020, 11, 8406-8416.
L.-M. Needham, J. Weber, J. A. Varela, J. W. B. Fyfe, D. T. Do, C. K. Xu, L. Tutton, R. Cliffe, B. Keenlyside, D. Klenerman, C. M. Dobson, C. A. Hunter, K. H. Müller, K. O'Holleran, S. E. Bohndiek, T. N. Snaddon, S. F. Lee, Chem. Sci. 2020, 11, 4578-4583.
C. Ran, X. Xu, S. B. Raymond, B. J. Ferrara, K. Neal, B. J. Bacskai, Z. Medarova, A. Moore, J. Am. Chem. Soc. 2009, 131, 15257-15261.
C. Peng, X. Wang, Y. Li, H. W. Li, M. S. Wong, J. Mater. Chem. B 2019, 7, 1986-1995.
J. Yang, F. Zeng, Y. Ge, K. Peng, X. Li, Y. Li, Y. Xu, Bioconjugate Chem. 2020, 31, 2-15.
B. Sot, A. Rubio-Muñoz, A. Leal-Quintero, J. Martínez-Sabando, M. Marcilla, C. Roodveldt, J. M. Valpuesta, Sci. Rep. 2017, 7, 40859-40870.
P. Bondia, J. Torra, C. M. Tone, T. Sawazaki, A. del Valle, B. Sot, S. Nonell, M. Kanai, Y. Sohma, C. Flors, J. Am. Chem. Soc. 2020, 142, 922-930.
R. Ni, A. Villois, X. L. Dean-Ben, Z. Chen, M. Vaas, S. Stavrakis, G. Shi, A. DeMello, C. Ran, D. Razansky, P. Arosio, J. Klohs, Photoacoustics 2021, 23, 100285-100296.
C. Spahn, J. B. Grimm, L. D. Lavis, M. Lampe, M. Heilemann, Nano Lett. 2019, 19, 500-505.
C. Spahn, F. Hurter, M. Glaesmann, C. Karathanasis, M. Lampe, M. Heilemann, Angew. Chem. Int. Ed. 2019, 58, 18835-18838;
Angew. Chem. 2019, 131, 19011-19014.
M. M. Perfilov, A. S. Gavrikov, K. A. Lukyanov, A. S. Mishin, Int. J. Mol. Sci. 2021, 22, 11799-11816.
R. Kasper, B. Harke, C. Forthmann, P. Tinnefeld, S. W. Hell, M. Sauer, Small 2010, 6, 1379-1384.
A. Sharonov, R. M. Hochstrasser, Proc. Natl. Acad. Sci. USA 2006, 103, 18911-18916.
N. Banterle, K. H. Bui, E. A. Lemke, M. Beck, J. Struct. Biol. 2013, 183, 363-367.
A. Monserrate, S. Casado, C. Flors, ChemPhysChem 2014, 15, 647-650.
P. Bondia, R. Jurado, S. Casado, J. M. Domínguez-Vera, N. Gálvez, C. Flors, Small 2017, 13, 1603784-1603790.
P. Bondia, S. Casado, C. Flors, Methods Mol. Biol. 2017, 1663, 105-113.
M. Cosentino, C. Canale, P. Bianchini, A. Diaspro, Sci. Adv. 2019, 5, eaav8062.
H. Mazidi, T. Ding, A. Nehorai, M. D. Lew, Nat. Commun. 2020, 11, 6353-6363.
M. Glogger, C. Spahn, J. Enderlein, M. Heilemann, Angew. Chem. 2021, 133, 6380-6383;
Angew. Chem. Int. Ed. 2021, 60, 6310-6313.
H. Liu, J. H. Naismith, BMC Biotechnol. 2008, 8, 91-100.
R. P. J. Nieuwenhuizen, K. A. Lidke, M. Bates, D. L. Puig, D. Grünwald, S. Stallinga, B. Rieger, Nat. Methods 2013, 10, 557-562.