Single-atom substitution enables supramolecular diversity from dipeptide building blocks.

Circular Dichroism Dipeptides / chemistry Hydrogels / chemistry Microscopy, Electron, Transmission Phenylalanine / chemistry

Journal

Soft matter
ISSN: 1744-6848
Titre abrégé: Soft Matter
Pays: England
ID NLM: 101295070

Informations de publication

Date de publication:
16 Mar 2022
Historique:
pubmed: 19 2 2022
medline: 18 3 2022
entrez: 18 2 2022
Statut: epublish

Résumé

Dipeptides are popular building blocks for supramolecular gels that do not persist in the environment and may find various applications. In this work, we show that a simple substitution on the aromatic side-chain of phenylalanine with either fluorine or iodine enables supramolecular diversity upon self-assembly at neutral pH, leading to hydrogels or crystals. Each building block is characterized by

Identifiants

DOI: 10.1039/d1sm01824h PMID: 35179536
pubmed: 35179536
doi: 10.1039/d1sm01824h
doi:

Substances chimiques

Dipeptides 0
Hydrogels 0
Phenylalanine 47E5O17Y3R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2129-2136

Auteurs

Erica Scarel (E)

University of Trieste, Chem. Pharm. Sc. Dept., Via Giorgieri 1, 34127 Trieste, Italy. smarchesan@units.it.
ORCID: 0000-0001-6854-482X

Ottavia Bellotto (O)

University of Trieste, Chem. Pharm. Sc. Dept., Via Giorgieri 1, 34127 Trieste, Italy. smarchesan@units.it.
ORCID: 0000-0003-4434-2865

Petr Rozhin (P)

University of Trieste, Chem. Pharm. Sc. Dept., Via Giorgieri 1, 34127 Trieste, Italy. smarchesan@units.it.

Slavko Kralj (S)

Jožef Stefan Institute, Materials Synthesis Dept., Jamova 39, 1000 Ljubljana, Slovenia.
University of Ljubljana, Pharmaceutical Technology Dept., Faculty of Pharmacy, Aškerčeva 7, 1000 Ljubljana, Slovenia.
ORCID: 0000-0002-9403-8274

Mariagrazia Tortora (M)

Area Science Park, Padriciano 99, 34149 Trieste, Italy.
Elettra-Sincrotrone Trieste, S.S. 114 km 163.5, Basovizza, 34149 Trieste, Italy. barbara.rossi@elettra.eu.
ORCID: 0000-0003-2149-3775

Attilio V Vargiu (AV)

University of Cagliari, Physics Dept., 09042 Monserrato, Cagliari, Italy.

Rita De Zorzi (R)

University of Trieste, Chem. Pharm. Sc. Dept., Via Giorgieri 1, 34127 Trieste, Italy. smarchesan@units.it.
ORCID: 0000-0001-7001-7498

Barbara Rossi (B)

Elettra-Sincrotrone Trieste, S.S. 114 km 163.5, Basovizza, 34149 Trieste, Italy. barbara.rossi@elettra.eu.
ORCID: 0000-0003-1357-8074

Silvia Marchesan (S)

University of Trieste, Chem. Pharm. Sc. Dept., Via Giorgieri 1, 34127 Trieste, Italy. smarchesan@units.it.
ORCID: 0000-0001-6089-3873

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Dichroïsme circulaire › Single-atom substitution enables...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Oligopeptides › Dipeptides › Single-atom substitution enables...
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › Single-atom substitution enables...
questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Microscopie électronique à transmission › Single-atom substitution enables...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés essentiels › Phénylalanine › Single-atom substitution enables...