Sublingual Misoprostol versus Oxytocin to Induce Labor in Term Premature Rupture of Membranes in Pregnant Women: A Randomized Single-Blind Controlled Trial.
Administration, Intravenous
Administration, Sublingual
Adult
Female
Fetal Membranes, Premature Rupture
Humans
Infant, Newborn
Labor, Induced
/ methods
Misoprostol
/ administration & dosage
Oxytocics
/ administration & dosage
Oxytocin
/ administration & dosage
Pregnancy
Pregnancy Outcome
Single-Blind Method
Thailand
Journal
BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173
Informations de publication
Date de publication:
2022
2022
Historique:
received:
16
09
2021
revised:
12
11
2021
accepted:
26
01
2022
entrez:
24
2
2022
pubmed:
25
2
2022
medline:
29
3
2022
Statut:
epublish
Résumé
The aim of this study was to compare maternal and neonatal outcomes between sublingual misoprostol and oxytocin on stimulating labor in term premature rupture of membranes (PROM) in pregnant women. A total of 170 women were enrolled and equally divided into study and control groups. Mean maternal age, body mass index, parity, gestational age, and bishop score of both groups were comparable. Induction time of the study group was statistically shorter than the control group (338 and 399 min, respectively). Duration of active phase (450/427 min) and the second stage (19/21 min) of labor between study and control groups were not significantly different. Cesarean section delivery rate of study was lower than the control group (13.3 and 28.8%, Induction time and cesarean section rates of sublingual misoprostol group were significantly lower than the intravenous oxytocin group in full-term PROM pregnancy.
Identifiants
pubmed: 35198639
doi: 10.1155/2022/9449036
pmc: PMC8858716
doi:
Substances chimiques
Oxytocics
0
Misoprostol
0E43V0BB57
Oxytocin
50-56-6
Types de publication
Comparative Study
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
9449036Informations de copyright
Copyright © 2022 Suchada Unthanan et al.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
J Obstet Gynaecol. 2020 Jan;40(1):20-24
pubmed: 31195867
Obstet Gynecol. 2009 Jul;114(1):192-202
pubmed: 19546798
Int J Gynaecol Obstet. 2007 Dec;99 Suppl 2:S160-7
pubmed: 17963768
Rev Bras Ginecol Obstet. 2013 Feb;35(2):60-5
pubmed: 23412004
Obstet Gynecol. 2009 Aug;114(2 Pt 1):386-397
pubmed: 19623003
Am J Perinatol. 2021 Feb;38(3):224-230
pubmed: 31491801
J Matern Fetal Neonatal Med. 2021 Feb;34(4):493-499
pubmed: 31006282
SAGE Open Med. 2017 Mar 23;5:2050312117700809
pubmed: 28540049
J Matern Fetal Neonatal Med. 2006 May;19(5):283-7
pubmed: 16753768
J Obstet Gynaecol. 2018 Feb;38(2):167-171
pubmed: 28784054