Modulation by Phosphonium Ions of the Activity of Mitotropic Agents Based on the Chemiluminescence of Luminols.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
12 Feb 2022
Historique:
received: 19 01 2022
revised: 08 02 2022
accepted: 10 02 2022
entrez: 25 2 2022
pubmed: 26 2 2022
medline: 5 3 2022
Statut: epublish

Résumé

Mitochondria-targeting drugs and diagnostics are used in the monitoring and treatment of mitochondrial pathologies. In this respect, a great number of functional compounds have been made mitotropic by covalently attaching the active moiety onto a triphenylphosphonium (

Identifiants

pubmed: 35209033
pii: molecules27041245
doi: 10.3390/molecules27041245
pmc: PMC8877776
pii:
doi:

Substances chimiques

Organophosphorus Compounds 0
Reactive Oxygen Species 0
Luminol 5EXP385Q4F

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : European Union's Horizon 2020 framework program for research and innovation
ID : 712921
Organisme : Generalitat Valenciana
ID : 2017/075
Organisme : State Scholarships Foundation
ID : 2016/35
Organisme : State Scholarships Foundation
ID : 2018/82

Références

Curr Opin Chem Biol. 2010 Feb;14(1):50-6
pubmed: 19910238
Chem Soc Rev. 2011 Sep;40(9):4783-804
pubmed: 21629957
Redox Biol. 2020 Oct;37:101690
pubmed: 33039825
Appl Biochem Biotechnol. 2014 May;173(2):333-55
pubmed: 24752935
Acc Chem Res. 2008 Jan;41(1):87-97
pubmed: 18193822
Biochem J. 2009 Jan 1;417(1):1-13
pubmed: 19061483
Nat Med. 2013 Apr;19(4):500-5
pubmed: 23455711
Science. 1998 Aug 28;281(5381):1309-12
pubmed: 9721092
Talanta. 2000 Mar 6;51(3):415-39
pubmed: 18967873
Chem Rev. 2017 Aug 9;117(15):10043-10120
pubmed: 28654243
Apoptosis. 2007 May;12(5):913-22
pubmed: 17453160
J Control Release. 2015 Jun 10;207:40-58
pubmed: 25841699
Anal Chim Acta. 2010 Apr 14;665(1):74-8
pubmed: 20381693
Chemistry. 2015 Jul 6;21(28):9975-9
pubmed: 26041370
Pharmacol Rev. 2002 Mar;54(1):101-27
pubmed: 11870261
J Mater Chem B. 2021 Jan 28;9(4):908-920
pubmed: 33346307
J Control Release. 2016 Oct 28;240:38-51
pubmed: 26482081
Chem Soc Rev. 2020 Oct 7;49(19):6800-6815
pubmed: 32929428
Molecules. 2020 Nov 11;25(22):
pubmed: 33187225
ACS Chem Biol. 2014 Feb 21;9(2):323-33
pubmed: 24410267
Nat Med. 2009 Apr;15(4):455-61
pubmed: 19305414
Nat Commun. 2019 Apr 12;10(1):1704
pubmed: 30979885
Antioxid Redox Signal. 2011 Dec 15;15(12):3021-38
pubmed: 21395490
J Org Chem. 2021 Sep 3;86(17):11388-11398
pubmed: 34350754
Molecules. 2019 Oct 31;24(21):
pubmed: 31683732
Nat Rev Mol Cell Biol. 2020 Feb;21(2):85-100
pubmed: 31636403

Auteurs

Gemma M Rodríguez-Muñiz (GM)

Instituto de Tecnología Química UPV-CSIC, Universitat Politècnica de València, Camino de Vera s/n, 46022 València, Spain.

Theodoros Mikroulis (T)

Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.

Anna Pantelia (A)

Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.

Georgios Rotas (G)

Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.

Maria-Consuelo Cuquerella (MC)

Instituto de Tecnología Química UPV-CSIC, Universitat Politècnica de València, Camino de Vera s/n, 46022 València, Spain.

Georgios C Vougioukalakis (GC)

Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.

Miguel A Miranda (MA)

Instituto de Tecnología Química UPV-CSIC, Universitat Politècnica de València, Camino de Vera s/n, 46022 València, Spain.

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Classifications MeSH