Regionally selective cardiovascular responses to adenosine A

Adenosine / analogs & derivatives Adenosine A2 Receptor Agonists / pharmacology Aminopyridines / pharmacology Animals HEK293 Cells Hemodynamics / drug effects Humans Kidney / blood supply Male Phenethylamines / pharmacology Pyrimidines / pharmacology Rats Rats, Sprague-Dawley Receptor, Adenosine A2A / physiology Receptor, Adenosine A2B / physiology Triazoles / pharmacology Vasodilation / drug effects Xanthines / pharmacology
A2 receptor activation Doppler flow adenosine hemodynamics

Journal

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484

Informations de publication

Date de publication:
04 2022
Historique:
revised: 31 01 2022
received: 19 12 2021
accepted: 07 02 2022
entrez: 1 3 2022
pubmed: 2 3 2022
medline: 11 3 2022
Statut: ppublish

Résumé

Adenosine is a local mediator that regulates changes in the cardiovascular system via activation of four G protein-coupled receptors (A

Identifiants

DOI: 10.1096/fj.202101945R PMID: 35230706 PMC: PMC9415116
pubmed: 35230706
doi: 10.1096/fj.202101945R
pmc: PMC9415116
doi:

Substances chimiques

1-propyl-8-(4-sulfophenyl)xanthine 0
5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine 0
Adenosine A2 Receptor Agonists 0
Aminopyridines 0
BAY 60-6583 0
Phenethylamines 0
Pyrimidines 0
Receptor, Adenosine A2A 0
Receptor, Adenosine A2B 0
Triazoles 0
Xanthines 0
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine 120225-54-9
Adenosine K72T3FS567

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e22214

Subventions

Organisme : British Heart Foundation
ID : PG/14/95/31248
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N020081/1
Pays : United Kingdom

Informations de copyright

© 2022 Federation of American Societies for Experimental Biology.

Références

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Auteurs

Samantha L Cooper (SL)

Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK.
Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, Midlands, UK.

Edward S Wragg (ES)

Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK.
Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, Midlands, UK.

Patrizia Pannucci (P)

Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK.
Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, Midlands, UK.

Mark Soave (M)

Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK.
Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, Midlands, UK.

Stephen J Hill (SJ)

Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK.
Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, Midlands, UK.
ORCID: 0000-0002-4424-239X

Jeanette Woolard (J)

Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK.
Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, Midlands, UK.
ORCID: 0000-0001-5406-6847

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Classifications MeSH

questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléosides › Ribonucléosides › Adénosine › Regionally selective cardiovascular responses...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents purinergiques › Agonistes purinergiques › Agonistes des récepteurs purinergiques P1 › Agonistes des récepteurs A2 à l'adénosine › Regionally selective cardiovascular responses...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyridines › Aminopyridines › Regionally selective cardiovascular responses...
questionsmedicales.fr › Eucaryotes › Animaux › Regionally selective cardiovascular responses...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › Regionally selective cardiovascular responses...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Hémodynamique › Regionally selective cardiovascular responses...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Regionally selective cardiovascular responses...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Regionally selective cardiovascular responses...
questionsmedicales.fr › Composés chimiques organiques › Amines › Éthylamines › Phénéthylamines › Regionally selective cardiovascular responses...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrimidines › Regionally selective cardiovascular responses...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Regionally selective cardiovascular responses...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Sprague-Dawley › Regionally selective cardiovascular responses...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs purinergiques › Récepteurs purinergiques P1 › Récepteurs A2 à l'adénosine › Récepteur A2A à l'adénosine › Regionally selective cardiovascular responses...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs purinergiques › Récepteurs purinergiques P1 › Récepteurs A2 à l'adénosine › Récepteur A2B à l'adénosine › Regionally selective cardiovascular responses...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Triazoles › Regionally selective cardiovascular responses...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Hémodynamique › Vasodilatation › Regionally selective cardiovascular responses...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Purines › Purinones › Xanthines › Regionally selective cardiovascular responses...