Derivatives of Natural Organocatalytic Cofactors and Artificial Organocatalytic Cofactors as Catalysts in Enzymes.
Journal
Chembiochem : a European journal of chemical biology
ISSN: 1439-7633
Titre abrégé: Chembiochem
Pays: Germany
ID NLM: 100937360
Informations de publication
Date de publication:
05 07 2022
05 07 2022
Historique:
revised:
14
03
2022
received:
31
10
2021
pubmed:
19
3
2022
medline:
7
7
2022
entrez:
18
3
2022
Statut:
ppublish
Résumé
Catalytically active non-metal cofactors in enzymes carry out a variety of different reactions. The efforts to develop derivatives of naturally occurring cofactors such as flavins or pyridoxal phosphate and the advances to design new, non-natural cofactors are reviewed here. We report the status quo for enzymes harboring organocatalysts as derivatives of natural cofactors or as artificial ones and their application in the asymmetric synthesis of various compounds.
Identifiants
pubmed: 35302276
doi: 10.1002/cbic.202100599
pmc: PMC9401024
doi:
Substances chimiques
Flavins
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202100599Informations de copyright
© 2022 The Authors. ChemBioChem published by Wiley-VCH GmbH.
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