Biological investigation of


Journal

Journal of enzyme inhibition and medicinal chemistry
ISSN: 1475-6374
Titre abrégé: J Enzyme Inhib Med Chem
Pays: England
ID NLM: 101150203

Informations de publication

Date de publication:
Dec 2022
Historique:
entrez: 24 3 2022
pubmed: 25 3 2022
medline: 29 3 2022
Statut: ppublish

Résumé

The enormous burden of the COVID-19 pandemic in economic and healthcare terms has cast a shadow on the serious threat of antimicrobial resistance, increasing the inappropriate use of antibiotics and shifting the focus of drug discovery programmes from antibacterial and antifungal fields. Thus, there is a pressing need for new antimicrobials involving innovative modes of action (MoAs) to avoid cross-resistance rise. Thiosemicarbazones (TSCs) stand out due to their easy preparation and polypharmacological application, also in infectious diseases. Recently, we reported a small library of TSCs (

Identifiants

pubmed: 35322729
doi: 10.1080/14756366.2022.2055009
pmc: PMC8956313
doi:

Substances chimiques

Anti-Infective Agents 0
Carbonic Anhydrase Inhibitors 0
Thiosemicarbazones 0
Carbonic Anhydrases EC 4.2.1.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

986-993

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Auteurs

Ilaria D'Agostino (I)

Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.

Githa Elizabeth Mathew (GE)

Department of Pharmacology, Grace College of Pharmacy, Palakkad, India.

Paola Angelini (P)

Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.

Roberto Venanzoni (R)

Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.

Giancarlo Angeles Flores (G)

Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.

Andrea Angeli (A)

Neurofarba Department, University of Florence, Sesto Fiorentino, Italy.

Simone Carradori (S)

Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.

Beatrice Marinacci (B)

Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.

Luigi Menghini (L)

Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.

Mohamed A Abdelgawad (MA)

Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.

Mohammed M Ghoneim (MM)

Department of Pharmacy Practice, Faculty of Pharmacy, AlMaarefa University, Ad Diriyah, Saudi Arabia.

Bijo Mathew (B)

Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, India.

Claudiu T Supuran (CT)

Neurofarba Department, University of Florence, Sesto Fiorentino, Italy.

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Classifications MeSH