Stimulation of G

Animals Eating Energy Metabolism GTP-Binding Proteins / metabolism Locomotion Mice Obesity / metabolism Receptor, Melanocortin, Type 4 / genetics
DREADD MC4R appetite cAMP energy expenditure

Journal

American journal of physiology. Endocrinology and metabolism
ISSN: 1522-1555
Titre abrégé: Am J Physiol Endocrinol Metab
Pays: United States
ID NLM: 100901226

Informations de publication

Date de publication:
01 05 2022
Historique:
pubmed: 29 3 2022
medline: 27 4 2022
entrez: 28 3 2022
Statut: ppublish

Résumé

The melanocortin 4 receptor (MC4R) plays an important role in the regulation of appetite and energy expenditure in humans and rodents. Impairment of MC4R signaling causes severe obesity. MC4R mainly couples to the G-protein G

Identifiants

DOI: 10.1152/ajpendo.00439.2021 PMID: 35344393
pubmed: 35344393
doi: 10.1152/ajpendo.00439.2021
doi:

Substances chimiques

MC4R protein, mouse 0
Receptor, Melanocortin, Type 4 0
GTP-Binding Proteins EC 3.6.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

E436-E445

Auteurs

Shigenobu Matsumura (S)

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
Department of Clinical Nutrition, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Osaka, Japan.
ORCID: 0000-0002-7149-1375

Motoki Miyakita (M)

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

Haruka Miyamori (H)

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

Satomi Kyo (S)

Department of Food and Nutrition, Kyoto Women's University, Kyoto, Japan.

Daisuke Shima (D)

Department of Food Sciences and Human Nutrition, Faculty of Agriculture, Ryukoku University, Shiga, Japan.

Takumi Yokokawa (T)

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

Fuka Ishikawa (F)

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

Tsutomu Sasaki (T)

Department of Neurology, Graduate School of Medicine, Osaka University, Osaka, Japan.

Tomoki Jinno (T)

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

Jin Tanaka (J)

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

Tsuyoshi Goto (T)

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

Keiko Momma (K)

Department of Food and Nutrition, Kyoto Women's University, Kyoto, Japan.

Kengo Ishihara (K)

Department of Food Sciences and Human Nutrition, Faculty of Agriculture, Ryukoku University, Shiga, Japan.

Rebecca Berdeaux (R)

Department of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas.
ORCID: 0000-0002-9929-1711

Kazuo Inoue (K)

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
ORCID: 0000-0001-7003-8635

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Stimulation of G
questionsmedicales.fr › Phénomènes physiologiques de l'appareil buccodentaire et de l'appareil digestif › Phénomènes physiologiques de l'appareil digestif › Consommation alimentaire › Stimulation of G
questionsmedicales.fr › Métabolisme › Métabolisme énergétique › Stimulation of G
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines G › Stimulation of G
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Mouvement › Locomotion › Stimulation of G
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Stimulation of G
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › Stimulation of G
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur hormone hypophysaire › Récepteur corticotrophine › Récepteurs à la mélanocortine › Récepteur de la mélanocortine de type 4 › Stimulation of G