Tail-approach based design and synthesis of Arylthiazolylhydrazono-1,2,3-triazoles incorporating sulfanilamide and metanilamide as human carbonic anhydrase I, II, IV and IX inhibitors.
1,2,3-triazole
Benzenesulfonamide
Carbonic anhydrase inhibitors
SLC-0111
Tail-approach
hCA isoforms
Journal
Bioorganic chemistry
ISSN: 1090-2120
Titre abrégé: Bioorg Chem
Pays: United States
ID NLM: 1303703
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
received:
21
02
2022
revised:
23
03
2022
accepted:
24
03
2022
pubmed:
3
4
2022
medline:
3
5
2022
entrez:
2
4
2022
Statut:
ppublish
Résumé
A library of twenty-two arylthiazolylhydrazono-1,2,3-triazoles incorporating sulfanilamide and metanilamide moieties have been synthesized by utilizing tail-approach and characterized by their IR,
Identifiants
pubmed: 35366582
pii: S0045-2068(22)00169-9
doi: 10.1016/j.bioorg.2022.105764
pii:
doi:
Substances chimiques
Antigens, Neoplasm
0
Carbonic Anhydrase Inhibitors
0
Sulfonamides
0
Triazoles
0
Sulfanilamide
21240MF57M
Carbonic Anhydrase I
EC 4.2.1.-
Carbonic Anhydrase II
EC 4.2.1.-
Carbonic Anhydrase IV
EC 4.2.1.-
CA1 carbonic anhydrase, human
EC 4.2.1.1
CA2 protein, human
EC 4.2.1.1
CA4 protein, human
EC 4.2.1.1
CA9 protein, human
EC 4.2.1.1
Carbonic Anhydrase IX
EC 4.2.1.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105764Informations de copyright
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