Hormetic Effect of 3-Bromopyruvate on Age-Induced Alterations in Erythrocyte Membrane Transporters and Oxidative Biomarkers in Rats.
3-bromopyruvate
aging
erythrocyte membrane
hormetic
transporters
Journal
Rejuvenation research
ISSN: 1557-8577
Titre abrégé: Rejuvenation Res
Pays: United States
ID NLM: 101213381
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
pubmed:
5
4
2022
medline:
22
6
2022
entrez:
4
4
2022
Statut:
ppublish
Résumé
3-Bromopyruvate (3-BP) is a glycolytic inhibitor and a potential calorie restriction mimic that shows a variety of beneficial effects in several aging model systems. A chronic low dose of 3-BP was given to male Wistar rats for 4 weeks. The effect of 3-BP on age-dependent alteration on the activities of various transporters/exchangers and redox biomarkers (protein carbonyl [PC], sialic acid [SA], sulfhydryl group [-SH], intracellular calcium ion [Ca
Identifiants
pubmed: 35373604
doi: 10.1089/rej.2021.0060
doi:
Substances chimiques
Biomarkers
0
Membrane Transport Proteins
0
Pyruvates
0
bromopyruvate
63JMV04GRK
Adenosine Triphosphatases
EC 3.6.1.-
N-Acetylneuraminic Acid
GZP2782OP0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM