Characterization of cord blood CD3
Cord blood
ILC
IUGR
MAIT
diabetes
hypertension
morbidly adherent placenta
Journal
American journal of reproductive immunology (New York, N.Y. : 1989)
ISSN: 1600-0897
Titre abrégé: Am J Reprod Immunol
Pays: Denmark
ID NLM: 8912860
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
revised:
07
03
2022
received:
03
03
2021
accepted:
12
04
2022
pubmed:
23
4
2022
medline:
1
7
2022
entrez:
22
4
2022
Statut:
ppublish
Résumé
Although pregnant women with gestational diabetes (GD), morbidly adherent placenta (MAP), and pregnancy hypertension (pHT) diseases lead to intrauterine growth restriction (IUGR), little is known about their effect on mucosal-associated invariant T (MAIT) and innate lymphoid cells (ILC) in the umbilical cord. This study aimed to quantify and characterize MAIT cells and ILCs in the cord blood of pregnant women with GD, MAP, and pHT diseases. Cord blood mononuclear cells (CBMCs) were isolated by Ficoll-Paque gradient. CD3 Compared with healthy pregnancies, in the cord blood of the pHT group, elevated number of lymphocytes was observed. Moreover, the absolute number of IFN-γ producing CD4 CD3
Substances chimiques
Granzymes
EC 3.4.21.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13555Informations de copyright
© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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