Hypocapnia in early hours of life is associated with brain injury in moderate to severe neonatal encephalopathy.
Journal
Journal of perinatology : official journal of the California Perinatal Association
ISSN: 1476-5543
Titre abrégé: J Perinatol
Pays: United States
ID NLM: 8501884
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
received:
05
12
2021
accepted:
08
04
2022
revised:
04
04
2022
pubmed:
25
4
2022
medline:
9
7
2022
entrez:
24
4
2022
Statut:
ppublish
Résumé
To evaluate the association between hypocapnia within the first 24 h of life and brain injury assessed by a detailed MRI scoring system in infants receiving therapeutic hypothermia (TH) for neonatal encephalopathy (NE) stratified by the stage of NE. This retrospective cohort study included infants who received TH for mild to severe NE. 188 infants were included in the study with 48% having mild and 52% moderate-severe NE. Infants with moderate-severe NE spent more time in hypocapnia (PCO In infants with moderate-severe NE, the hours spent in hypocapnia was an independent predictor of brain injury.
Identifiants
pubmed: 35461333
doi: 10.1038/s41372-022-01398-2
pii: 10.1038/s41372-022-01398-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
892-897Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature America, Inc.
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