The effect of cannabinoid receptor agonist WIN 55,212-2 on anxiety-like behavior and locomotion in a genetic model of absence seizures in the elevated plus-maze.


Journal

CNS neuroscience & therapeutics
ISSN: 1755-5949
Titre abrégé: CNS Neurosci Ther
Pays: England
ID NLM: 101473265

Informations de publication

Date de publication:
08 2022
Historique:
revised: 04 04 2022
received: 08 03 2022
accepted: 07 04 2022
pubmed: 27 4 2022
medline: 8 7 2022
entrez: 26 4 2022
Statut: ppublish

Résumé

GAERS and NEC rats were treated with cannabinoid 1/2 receptor agonist WIN 55,212-2 2 mg/kg and tested on the Elevated Plus-Maze.

Identifiants

pubmed: 35470960
doi: 10.1111/cns.13848
pmc: PMC9253729
doi:

Substances chimiques

Benzoxazines 0
Cannabinoid Receptor Agonists 0
Morpholines 0
Naphthalenes 0
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone 5H31GI9502

Types de publication

Letter Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1268-1270

Informations de copyright

© 2022 The Authors. CNS Neuroscience & Therapeutics Published by John Wiley & Sons Ltd.

Références

Epilepsy Behav. 2020 Jan;102:106722
pubmed: 31855784
Epilepsia. 2014 Sep;55(9):1460-8
pubmed: 25059093
Neuropharmacology. 2021 Jun 1;190:108553
pubmed: 33845076
Epilepsia. 2021 May;62(5):1041-1056
pubmed: 33751566
Epilepsia. 2010 Aug;51(8):1511-21
pubmed: 20132294
Neuropharmacology. 2016 Sep;108:292-304
pubmed: 27085605
Epilepsy Res. 1991 Jul;9(2):97-104
pubmed: 1794357
Brain. 2020 Aug 1;143(8):2341-2368
pubmed: 32437558
Eur J Neurosci. 2016 Jan;43(1):25-40
pubmed: 26490879
Neurobiol Dis. 2010 Jul;39(1):116-25
pubmed: 20153428
Eur J Pharmacol. 2007 Jun 1;563(1-3):141-8
pubmed: 17374533
Prog Brain Res. 2021;259:83-134
pubmed: 33541682

Auteurs

Daniel Cassar (D)

Laboratory of Neurophysiology, Department of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.

Manuela Radic (M)

Laboratory of Neurophysiology, Department of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.

Maurizio Casarrubea (M)

Laboratory of Behavioral Physiology, Human Physiology Section "Giuseppe Pagano", Department of Biomedicine, Neuroscience and Advanced Diagnosistics (BIND), University of Palermo, Palermo, Italy.

Vincenzo Crunelli (V)

Neuroscience Division, School of Biosciences, Cardiff University, Cardiff, UK.

Giuseppe Di Giovanni (G)

Laboratory of Neurophysiology, Department of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.
Neuroscience Division, School of Biosciences, Cardiff University, Cardiff, UK.

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Classifications MeSH