CD66b


Journal

Nature immunology
ISSN: 1529-2916
Titre abrégé: Nat Immunol
Pays: United States
ID NLM: 100941354

Informations de publication

Date de publication:
05 2022
Historique:
received: 31 05 2021
accepted: 15 03 2022
pubmed: 29 4 2022
medline: 18 5 2022
entrez: 28 4 2022
Statut: ppublish

Résumé

Here we report the identification of human CD66b

Identifiants

pubmed: 35484408
doi: 10.1038/s41590-022-01189-z
pii: 10.1038/s41590-022-01189-z
doi:

Substances chimiques

Antigens, CD 0
CEACAM8 protein, human 0
Cell Adhesion Molecules 0
GPI-Linked Proteins 0
Receptors, IgG 0
Interferons 9008-11-1
Receptor, Macrophage Colony-Stimulating Factor EC 2.7.10.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

679-691

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature America, Inc.

Références

Notta, F. et al. Distinct routes of lineage development reshape the human blood hierarchy across ontogeny. Science 351, aab2116 (2016).
pubmed: 26541609 doi: 10.1126/science.aab2116
Paul, F. et al. Transcriptional heterogeneity and lineage commitment in myeloid progenitors. Cell 163, 1663–1677 (2015).
pubmed: 26627738 doi: 10.1016/j.cell.2015.11.013
Velten, L. et al. Human haematopoietic stem cell lineage commitment is a continuous process. Nat. Cell Biol. 19, 271–281 (2017).
pubmed: 28319093 pmcid: 5496982 doi: 10.1038/ncb3493
Pellin, D. et al. A comprehensive single cell transcriptional landscape of human hematopoietic progenitors. Nat. Commun. 10, 2395 (2019).
pubmed: 31160568 pmcid: 6546699 doi: 10.1038/s41467-019-10291-0
Yanez, A. et al. Granulocyte-monocyte progenitors and monocyte-dendritic cell progenitors independently produce functionally distinct monocytes. Immunity 47, 890–902.e4 (2017).
pubmed: 29166589 pmcid: 5726802 doi: 10.1016/j.immuni.2017.10.021
Zheng, S. et al. Molecular transitions in early progenitors during human cord blood hematopoiesis. Mol. Syst. Biol. 14, e8041 (2018).
pubmed: 29545397 pmcid: 5852373 doi: 10.15252/msb.20178041
Karamitros, D. et al. Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells. Nat. Immunol. 19, 85–97 (2018).
pubmed: 29167569 doi: 10.1038/s41590-017-0001-2
Weinreb, C., Rodriguez-Fraticelli, A., Camargo, F. D. & Klein, A. M. Lineage tracing on transcriptional landscapes links state to fate during differentiation. Science 367, eaaw3381 (2020).
pubmed: 31974159 pmcid: 7608074 doi: 10.1126/science.aaw3381
Muench, D. E. et al. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature 582, 109–114 (2020).
pubmed: 32494068 pmcid: 8041154 doi: 10.1038/s41586-020-2227-7
Doulatov, S., Notta, F., Laurenti, E. & Dick, J. E. Hematopoiesis: a human perspective. Cell Stem Cell 10, 120–136 (2012).
pubmed: 22305562 doi: 10.1016/j.stem.2012.01.006
Watcham, S., Kucinski, I. & Gottgens, B. New insights into hematopoietic differentiation landscapes from single-cell RNA sequencing. Blood 133, 1415–1426 (2019).
pubmed: 30728144 pmcid: 6440294 doi: 10.1182/blood-2018-08-835355
Jacobsen, S. E. W. & Nerlov, C. Haematopoiesis in the era of advanced single-cell technologies. Nat. Cell Biol. 21, 2–28 (2019).
pubmed: 30602765 doi: 10.1038/s41556-018-0227-8
Manz, M. G., Miyamoto, T., Akashi, K. & Weissman, I. L. Prospective isolation of human clonogenic common myeloid progenitors. Proc. Natl Acad. Sci. USA 99, 11872–11877 (2002).
pubmed: 12193648 pmcid: 129361 doi: 10.1073/pnas.172384399
Doulatov, S. et al. Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development. Nat. Immunol. 11, 585–593 (2010).
pubmed: 20543838 doi: 10.1038/ni.1889
Lee, J. et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J. Exp. Med. 212, 385–399 (2015).
pubmed: 25687283 pmcid: 4354373 doi: 10.1084/jem.20141442
Kawamura, S. et al. Identification of a human clonogenic progenitor with strict monocyte differentiation potential: a counterpart of mouse cMoPs. Immunity 46, 835–848.e4 (2017).
pubmed: 28514689 doi: 10.1016/j.immuni.2017.04.019
Mori, Y. et al. Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor. J. Exp. Med. 206, 183–193 (2009).
pubmed: 19114669 pmcid: 2626675 doi: 10.1084/jem.20081756
Gorgens, A. et al. Revision of the human hematopoietic tree: granulocyte subtypes derive from distinct hematopoietic lineages. Cell Rep. 3, 1539–1552 (2013).
pubmed: 23707063 doi: 10.1016/j.celrep.2013.04.025
Drissen, R., Thongjuea, S., Theilgaard-Monch, K. & Nerlov, C. Identification of two distinct pathways of human myelopoiesis. Sci. Immunol. 4, eaau7148 (2019).
pubmed: 31126997 doi: 10.1126/sciimmunol.aau7148
Olweus, J., Thompson, P. A. & Lund-Johansen, F. Granulocytic and monocytic differentiation of CD34
pubmed: 8916938 doi: 10.1182/blood.V88.10.3741.bloodjournal88103741
Evrard, M. et al. Developmental analysis of bone marrow neutrophils reveals populations specialized in expansion, trafficking, and effector functions. Immunity 48, 364–379.e8 (2018).
pubmed: 29466759 doi: 10.1016/j.immuni.2018.02.002
Zhu, Y. P. et al. Identification of an early unipotent neutrophil progenitor with pro-tumoral activity in mouse and human bone marrow. Cell Rep. 24, 2329–2341.e8 (2018).
pubmed: 30157427 pmcid: 6542273 doi: 10.1016/j.celrep.2018.07.097
Kwok, I. et al. Combinatorial single-cell analyses of granulocyte-monocyte progenitor heterogeneity reveals an early uni-potent neutrophil progenitor. Immunity 53, 303–318.e5 (2020).
pubmed: 32579887 doi: 10.1016/j.immuni.2020.06.005
Dinh, H. Q. et al. Coexpression of CD71 and CD117 identifies an early unipotent neutrophil progenitor population in human bone marrow. Immunity 53, 319–334.e6 (2020).
pubmed: 32814027 pmcid: 7942809 doi: 10.1016/j.immuni.2020.07.017
Schulte-Schrepping, J. et al. Severe COVID-19 is marked by a dysregulated myeloid cell compartment. Cell 182, 1419–1440.e23 (2020).
pubmed: 32810438 pmcid: 7405822 doi: 10.1016/j.cell.2020.08.001
van Lochem, E. G. et al. Immunophenotypic differentiation patterns of normal hematopoiesis in human bone marrow: reference patterns for age-related changes and disease-induced shifts. Cytom. B Clin. Cytom. 60, 1–13 (2004).
Gorczyca, W. et al. Immunophenotypic pattern of myeloid populations by flow cytometry analysis. Methods Cell. Biol. 103, 221–266 (2011).
pubmed: 21722806 doi: 10.1016/B978-0-12-385493-3.00010-3
Olweus, J. et al. Dendritic cell ontogeny: a human dendritic cell lineage of myeloid origin. Proc. Natl Acad. Sci. USA 94, 12551–12556 (1997).
pubmed: 9356487 pmcid: 25034 doi: 10.1073/pnas.94.23.12551
Breton, G., Lee, J., Liu, K. & Nussenzweig, M. C. Defining human dendritic cell progenitors by multiparametric flow cytometry. Nat. Protoc. 10, 1407–1422 (2015).
pubmed: 26292072 pmcid: 4607256 doi: 10.1038/nprot.2015.092
Villani, A. C. et al. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Science 356, eaah4573 (2017).
pubmed: 28428369 pmcid: 5775029 doi: 10.1126/science.aah4573
See, P. et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science 356, eaag3009 (2017).
pubmed: 28473638 pmcid: 7611082 doi: 10.1126/science.aag3009
Lee, J. et al. Lineage specification of human dendritic cells is marked by IRF8 expression in hematopoietic stem cells and multipotent progenitors. Nat. Immunol. 18, 877–888 (2017).
pubmed: 28650480 pmcid: 5743223 doi: 10.1038/ni.3789
Olweus, J., Lund-Johansen, F. & Terstappen, L. W. Expression of cell surface markers during differentiation of CD34
pubmed: 7540098 doi: 10.1006/immu.1994.1054
Cowland, J. B. & Borregaard, N. Granulopoiesis and granules of human neutrophils. Immunol. Rev. 273, 11–28 (2016).
pubmed: 27558325 doi: 10.1111/imr.12440
Cassatella, M. A., Ostberg, N. K., Tamassia, N. & Soehnlein, O. Biological roles of neutrophil-derived granule proteins and cytokines. Trends Immunol. 40, 648–664 (2019).
pubmed: 31155315 doi: 10.1016/j.it.2019.05.003
Love, M. I., Huber, W. & Anders, S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 15, 550 (2014).
pubmed: 25516281 pmcid: 4302049 doi: 10.1186/s13059-014-0550-8
Mora-Jensen, H. et al. Technical advance: immunophenotypical characterization of human neutrophil differentiation. J. Leukoc. Biol. 90, 629–634 (2011).
pubmed: 21653237 doi: 10.1189/jlb.0311123
Elghetany, M. T. Surface antigen changes during normal neutrophilic development: a critical review. Blood Cells Mol. Dis. 28, 260–274 (2002).
pubmed: 12064921 doi: 10.1006/bcmd.2002.0513
Olweus, J., Lund-Johansen, F. & Terstappen, L. W. CD64/Fc gamma RI is a granulo-monocytic lineage marker on CD34
pubmed: 7537112 doi: 10.1182/blood.V85.9.2402.bloodjournal8592402
Gross, S. et al. Characterization and phenotypic analysis of differentiating CD34
pubmed: 9414644 doi: 10.1111/j.1600-0609.1997.tb01693.x
Becht, E. et al. Dimensionality reduction for visualizing single-cell data using UMAP. Nat. Biotechnol. 37, 38–44 (2018).
doi: 10.1038/nbt.4314
Hafemeister, C. & Satija, R. Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression. Genome Biol. 20, 296 (2019).
pubmed: 31870423 pmcid: 6927181 doi: 10.1186/s13059-019-1874-1
Angerer, P. et al. destiny: diffusion maps for large-scale single-cell data in R. Bioinformatics 32, 1241–1243 (2016).
pubmed: 26668002 doi: 10.1093/bioinformatics/btv715
Xie, X. et al. Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection. Nat. Immunol. 21, 1119–1133 (2020).
pubmed: 32719519 pmcid: 7442692 doi: 10.1038/s41590-020-0736-z
Gupta, S. et al. Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism. Proc. Natl Acad. Sci. USA 117, 16481–16491 (2020).
pubmed: 32601182 pmcid: 7368314 doi: 10.1073/pnas.2003603117
Zilionis, R. et al. Single-cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species. Immunity 50, 1317–1334.e1310 (2019).
pubmed: 30979687 pmcid: 6620049 doi: 10.1016/j.immuni.2019.03.009
Mistry, P. et al. Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus. Proc. Natl Acad. Sci. USA 116, 25222–25228 (2019).
pubmed: 31754025 pmcid: 6911190 doi: 10.1073/pnas.1908576116
Sinha, S. et al. Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19. Nat. Med. 28, 201–211 (2022).
pubmed: 34782790 doi: 10.1038/s41591-021-01576-3
Bost, P. et al. Deciphering the state of immune silence in fatal COVID-19 patients. Nat. Commun. 12, 1428 (2021).
pubmed: 33674591 pmcid: 7935849 doi: 10.1038/s41467-021-21702-6
Calzetti, F. et al. The importance of being “pure” neutrophils. J. Allergy Clin. Immunol. 139, 352–355.e6 (2017).
pubmed: 27567327 doi: 10.1016/j.jaci.2016.06.025
Zimmermann, M. et al. IFNɑ enhances the production of IL-6 by human neutrophils activated via TLR8. Sci. Rep. 6, 19674 (2016).
pubmed: 26790609 pmcid: 4726390 doi: 10.1038/srep19674
Tura, O. et al. Optimal ex vivo expansion of neutrophils from PBSC CD34
pubmed: 17971220 pmcid: 2174439 doi: 10.1186/1479-5876-5-53
Jie, Z. et al. Large-scale ex vivo generation of human neutrophils from cord blood CD34
pubmed: 28700636 pmcid: 5507460 doi: 10.1371/journal.pone.0180832
Serra, M. C., Calzetti, F., Ceska, M. & Cassatella, M. A. Effect of substance P on superoxide anion and IL-8 production by human PMNL. Immunology 82, 63–69 (1994).
pubmed: 7519174 pmcid: 1414864
Tamassia, N. et al. The MyD88-independent pathway is not mobilized in human neutrophils stimulated via TLR4. J. Immunol. 178, 7344–7356 (2007).
pubmed: 17513785 doi: 10.4049/jimmunol.178.11.7344
Picelli, S. et al. Full-length RNA-seq from single cells using Smart-seq2. Nat. Protoc. 9, 171–181 (2014).
pubmed: 24385147 doi: 10.1038/nprot.2014.006
Bianchetto-Aguilera, F. et al. Deciphering the fate of slan
pubmed: 32413173 doi: 10.1096/fj.202000181R
Hahsler, M., Hornik, K. & Buchta, C. Getting things in order: an introduction to the R package seriation. J. Stat. Softw. 25, 1–34 (2008).
doi: 10.18637/jss.v025.i03
Butler, A. et al. Integrating single-cell transcriptomic data across different conditions, technologies, and species. Nat. Biotechnol. 36, 411–420 (2018).
pubmed: 29608179 pmcid: 6700744 doi: 10.1038/nbt.4096
Yu, G., Wang, L. G., Han, Y. & He, Q. Y. clusterProfiler: an R package for comparing biological themes among gene clusters. OMICS 16, 284–287 (2012).
pubmed: 22455463 pmcid: 3339379 doi: 10.1089/omi.2011.0118

Auteurs

Federica Calzetti (F)

Section of General Pathology, Department of Medicine, University of Verona, Verona, Italy.

Giulia Finotti (G)

Section of General Pathology, Department of Medicine, University of Verona, Verona, Italy.

Nicola Tamassia (N)

Section of General Pathology, Department of Medicine, University of Verona, Verona, Italy.

Francisco Bianchetto-Aguilera (F)

Section of General Pathology, Department of Medicine, University of Verona, Verona, Italy.

Monica Castellucci (M)

Centro Piattaforme Tecnologiche, University of Verona, Verona, Italy.

Stefania Canè (S)

Section of Immunology, Department of Medicine, University of Verona, Verona, Italy.

Silvia Lonardi (S)

Unit of Pathology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.

Chiara Cavallini (C)

Interdepartmental Laboratory of Medical Research, Research Center LURM, University of Verona, Verona, Italy.

Alessandro Matte (A)

Section of Internal Medicine B, Department of Medicine, University of Verona and AOUI Verona, Verona, Italy.

Sara Gasperini (S)

Section of General Pathology, Department of Medicine, University of Verona, Verona, Italy.

Ilaria Signoretto (I)

Section of General Pathology, Department of Medicine, University of Verona, Verona, Italy.

Fabio Benedetti (F)

Section of Hematology and Bone Marrow Transplant Unit, Department of Medicine, University of Verona, Verona, Italy.

Massimiliano Bonifacio (M)

Section of Hematology and Bone Marrow Transplant Unit, Department of Medicine, University of Verona, Verona, Italy.

William Vermi (W)

Unit of Pathology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.

Stefano Ugel (S)

Section of Immunology, Department of Medicine, University of Verona, Verona, Italy.

Vincenzo Bronte (V)

Section of Immunology, Department of Medicine, University of Verona, Verona, Italy.

Cristina Tecchio (C)

Section of Hematology and Bone Marrow Transplant Unit, Department of Medicine, University of Verona, Verona, Italy.

Patrizia Scapini (P)

Section of General Pathology, Department of Medicine, University of Verona, Verona, Italy.

Marco A Cassatella (MA)

Section of General Pathology, Department of Medicine, University of Verona, Verona, Italy. marco.cassatella@univr.it.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH