Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening.


Journal

Journal of enzyme inhibition and medicinal chemistry
ISSN: 1475-6374
Titre abrégé: J Enzyme Inhib Med Chem
Pays: England
ID NLM: 101150203

Informations de publication

Date de publication:
Dec 2022
Historique:
entrez: 29 4 2022
pubmed: 30 4 2022
medline: 3 5 2022
Statut: ppublish

Résumé

An efficient method for synthesising NMDAR co-agonist Sunifiram (DM235), in addition to Sunifram-carbamate and anthranilamide hybrids, has been developed in high yields

Identifiants

pubmed: 35484855
doi: 10.1080/14756366.2022.2068147
pmc: PMC9067966
doi:

Substances chimiques

Carbamates 0
Cholinesterase Inhibitors 0
Nootropic Agents 0
Piperazines 0
Receptors, N-Methyl-D-Aspartate 0
DM 235 66924E735K
Donepezil 8SSC91326P
Acetylcholinesterase EC 3.1.1.7

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1241-1256

Références

J Enzyme Inhib Med Chem. 2016;31(2):187-94
pubmed: 25831025
Curr Pharm Biotechnol. 2016;17(14):1231-1245
pubmed: 27804852
Bio Protoc. 2013;3(24):
pubmed: 27390758
J Gen Physiol. 2015 Jun;145(6):513-27
pubmed: 25964432
J Cheminform. 2012 Aug 13;4(1):17
pubmed: 22889332
Neuropsychopharmacology. 2005 Mar;30(3):633-9
pubmed: 15647751
Expert Opin Investig Drugs. 2007 Jan;16(1):59-72
pubmed: 17155854
Acta Histochem. 2018 Apr;120(3):159-167
pubmed: 29496266
Methods Mol Biol. 2015;1263:243-50
pubmed: 25618350
Eur J Pharm Sci. 2002 Dec;17(4-5):253-63
pubmed: 12453615
J Med Chem. 2000 Nov 16;43(23):4499-507
pubmed: 11087574
Neural Plast. 2017;2017:2875904
pubmed: 28163934
Cancer Res. 2013 Feb 15;73(4):1328-39
pubmed: 23222296
Trends Neurosci. 1999 Jun;22(6):273-80
pubmed: 10354606
Sci Rep. 2018 Oct 8;8(1):14921
pubmed: 30297729
J Physiol. 2004 Jun 1;557(Pt 2):489-500
pubmed: 15064326
Pharmacol Rev. 1997 Dec;49(4):403-49
pubmed: 9443165
Biophys Rev. 2017 Apr;9(2):91-102
pubmed: 28510083
Arch Gen Psychiatry. 1995 Dec;52(12):998-1007
pubmed: 7492260
Biomed Pharmacother. 2014 May;68(4):493-6
pubmed: 24751001
Psychopharmacology (Berl). 2005 Dec;183(3):265-74
pubmed: 16220331
Lancet Psychiatry. 2020 Feb;7(2):191-207
pubmed: 31732482
J Med Chem. 2008 Jul 24;51(14):4200-12
pubmed: 18570368
Expert Opin Investig Drugs. 2014 Feb;23(2):243-54
pubmed: 24251380
Neuropharmacology. 2001 Jul;41(1):88-96
pubmed: 11445189
Neuroscience. 2006 Dec;143(3):671-8
pubmed: 17000053
Adv Drug Deliv Rev. 2001 Mar 1;46(1-3):3-26
pubmed: 11259830
CNS Drug Rev. 2006 Spring;12(1):39-52
pubmed: 16834757
Expert Rev Neurother. 2012 Nov;12(11):1351-65
pubmed: 23234396
J Med Chem. 2006 Aug 24;49(17):5051-8
pubmed: 16913695
J Med Chem. 2017 Nov 22;60(22):9097-9113
pubmed: 28609624
J Comput Chem. 2010 Jan 30;31(2):455-61
pubmed: 19499576
Biochem Pharmacol. 1961 Jul;7:88-95
pubmed: 13726518
Neurobiol Dis. 2004 Feb;15(1):80-92
pubmed: 14751773
J Clin Neurosci. 2007 Oct;14(10):919-27
pubmed: 17659875
Hippocampus. 2013 Oct;23(10):942-51
pubmed: 23733502
Curr Neuropharmacol. 2016;14(1):101-15
pubmed: 26813123
Iran J Pharm Res. 2015 Summer;14(3):949-54
pubmed: 26330885
Neuropharmacology. 2021 Jun 1;190:108352
pubmed: 33035532
Expert Opin Ther Pat. 2012 Nov;22(11):1337-52
pubmed: 23009122
Brain Res. 1998 Jun 8;795(1-2):215-20
pubmed: 9622635
Mol Med Rep. 2019 Aug;20(2):1479-1487
pubmed: 31257471
J Org Chem. 2011 Jun 17;76(12):4884-93
pubmed: 21452874
Neuropharmacology. 2013 Jan;64:13-26
pubmed: 22796429
Biochemistry. 2002 Mar 19;41(11):3555-64
pubmed: 11888271
Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jun 8;92:387-404
pubmed: 30738126
Bioorg Chem. 2021 Sep;114:105100
pubmed: 34246972
NeuroRx. 2005 Oct;2(4):541-53
pubmed: 16489364
J Pharmacopuncture. 2019 Dec;22(4):231-238
pubmed: 31970020
Curr Opin Investig Drugs. 2006 Jul;7(7):608-13
pubmed: 16869112

Auteurs

Khalid A Agha (KA)

Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, Fayoum University, Fayoum, Egypt.
Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Nader E Abo-Dya (NE)

Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia.

Abdul Rashid Issahaku (AR)

Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Clement Agoni (C)

Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Mahmoud E S Soliman (MES)

Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Eatedal H Abdel-Aal (EH)

Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Zakaria K Abdel-Samii (ZK)

Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Tarek S Ibrahim (TS)

Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.

Articles similaires

Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH