Relationships between food-related behaviors, obesity, and medication use in individuals with Smith-Magenis syndrome.


Journal

Research in developmental disabilities
ISSN: 1873-3379
Titre abrégé: Res Dev Disabil
Pays: United States
ID NLM: 8709782

Informations de publication

Date de publication:
Aug 2022
Historique:
received: 05 12 2021
revised: 01 04 2022
accepted: 29 04 2022
pubmed: 22 5 2022
medline: 22 6 2022
entrez: 21 5 2022
Statut: ppublish

Résumé

Smith-Magenis syndrome (SMS) is a complex neurodevelopmental disorder that includes obesity and food-seeking/satiety-related behaviors. This study examined associations between food-related/hyperphagic behaviors, weight, and medication use in individuals with SMS. Caregivers of individuals with SMS in the Parents and Researchers Interested in SMS (PRISMS) Patient Registry completed a demographic/medication questionnaire, the Hyperphagia Questionnaire for Clinical Trials, and the Food Related Problems Questionnaire. Among 49 participants (M Maladaptive food-related behaviors were higher in individuals with SMS with overweight/obesity, taking anti-depressants/anxiolytics, or who were male. Medications in this population should be chosen with weight-related side effects in mind.

Sections du résumé

BACKGROUND BACKGROUND
Smith-Magenis syndrome (SMS) is a complex neurodevelopmental disorder that includes obesity and food-seeking/satiety-related behaviors.
AIMS OBJECTIVE
This study examined associations between food-related/hyperphagic behaviors, weight, and medication use in individuals with SMS.
METHODS/PROCEDURES METHODS
Caregivers of individuals with SMS in the Parents and Researchers Interested in SMS (PRISMS) Patient Registry completed a demographic/medication questionnaire, the Hyperphagia Questionnaire for Clinical Trials, and the Food Related Problems Questionnaire.
OUTCOMES/RESULTS RESULTS
Among 49 participants (M
CONCLUSIONS/IMPLICATIONS CONCLUSIONS
Maladaptive food-related behaviors were higher in individuals with SMS with overweight/obesity, taking anti-depressants/anxiolytics, or who were male. Medications in this population should be chosen with weight-related side effects in mind.

Identifiants

pubmed: 35597045
pii: S0891-4222(22)00087-7
doi: 10.1016/j.ridd.2022.104257
pii:
doi:

Substances chimiques

Anti-Anxiety Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

104257

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Auteurs

Anusha A Gandhi (AA)

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

Theresa A Wilson (TA)

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

Stephanie Sisley (S)

Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA; Children's Nutrition Research Center, Houston, TX 77030, USA.

Sarah H Elsea (SH)

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: sarah.elsea@bcm.edu.

Rebecca H Foster (RH)

Department of Psychology, St. Louis Children's Hospital, St. Louis, MO 63110, USA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH